(3α,5α,6β,17β)-17-(benzyloxymethyl)-6-methoxy-3-(methoxymethoxy)-androstane

Base Information

Chemical Name:(3α,5α,6β,17β)-17-(benzyloxymethyl)-6-methoxy-3-(methoxymethoxy)-androstane
CAS No.:1624341-83-8
Molecular Formula:C₃₀H₄₆O₄
Molecular Weight:470.693
Hs Code.:

Synonyms:(3α,5α,6β,17β)-17-(benzyloxymethyl)-6-methoxy-3-(methoxymethoxy)-androstane

Suppliers and Price of (3α,5α,6β,17β)-17-(benzyloxymethyl)-6-methoxy-3-(methoxymethoxy)-androstane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (3α,5α,6β,17β)-17-(benzyloxymethyl)-6-methoxy-3-(methoxymethoxy)-androstane

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (3α,5α,6β,17β)-17-(benzyloxymethyl)-6-methoxy-3-(methoxymethoxy)-androstane

There total 11 articles about (3α,5α,6β,17β)-17-(benzyloxymethyl)-6-methoxy-3-(methoxymethoxy)-androstane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1624341-82-7
(3α,5α,6β,17β)-17-(benzyloxymethyl)-6-methoxy-androstan-3-ol

: 107-30-2
chloromethyl methyl ether

: 1624341-83-8
(3α,5α,6β,17β)-17-(benzyloxymethyl)-6-methoxy-3-(methoxymethoxy)-androstane

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 12h;

Reference yield:

: C₂₉H₄₄O₄

: 1624341-83-8
(3α,5α,6β,17β)-17-(benzyloxymethyl)-6-methoxy-3-(methoxymethoxy)-androstane

Guidance literature:: Multi-step reaction with 7 steps

1.1: pyridinium chlorochromate / dichloromethane / 4 h / 20 °C

1.2: 3 h / Reflux

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 20 °C

3.1: sodium hydride / tetrahydrofuran; mineral oil / 14 h / 60 °C

4.1: hydrogenchloride / water; methanol / 8 h / 20 °C

5.1: sulfuric acid; chromium(VI) oxide / [⁽²⁾H₆]acetone / 0 °C

6.1: potassium tri-sec-butyl-borohydride / tetrahydrofuran / 2 h / -78 °C

6.2: 2 h / 0 - 20 °C

7.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 12 h / 20 °C

With chromium(VI) oxide; hydrogenchloride; lithium aluminium tetrahydride; sulfuric acid; sodium hydride; potassium tri-sec-butyl-borohydride; N-ethyl-N,N-diisopropylamine; pyridinium chlorochromate; In tetrahydrofuran; methanol; [⁽²⁾H₆]acetone; dichloromethane; water; mineral oil;

Reference yield:

: 1624341-75-8
(3β,17β)-17-(benzyloxymethyl)-3-methoxymethoxy-androst-5-ene

: 1624341-83-8
(3α,5α,6β,17β)-17-(benzyloxymethyl)-6-methoxy-3-(methoxymethoxy)-androstane

Guidance literature:: Multi-step reaction with 8 steps

1.1: borane-THF / tetrahydrofuran / 3 h / 0 °C

1.2: 3 h / 20 °C

2.1: pyridinium chlorochromate / dichloromethane / 4 h / 20 °C

2.2: 3 h / Reflux

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 20 °C

4.1: sodium hydride / tetrahydrofuran; mineral oil / 14 h / 60 °C

5.1: hydrogenchloride / water; methanol / 8 h / 20 °C

6.1: sulfuric acid; chromium(VI) oxide / [⁽²⁾H₆]acetone / 0 °C

7.1: potassium tri-sec-butyl-borohydride / tetrahydrofuran / 2 h / -78 °C

7.2: 2 h / 0 - 20 °C

8.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 12 h / 20 °C

With chromium(VI) oxide; hydrogenchloride; lithium aluminium tetrahydride; borane-THF; sulfuric acid; sodium hydride; potassium tri-sec-butyl-borohydride; N-ethyl-N,N-diisopropylamine; pyridinium chlorochromate; In tetrahydrofuran; methanol; [⁽²⁾H₆]acetone; dichloromethane; water; mineral oil;