Urea, 1-(4,7-dimethoxy-6-(2-(diethylamino)ethoxy)-5-benzofuranyl)-3-methyl-

Base Information

Chemical Name:Urea, 1-(4,7-dimethoxy-6-(2-(diethylamino)ethoxy)-5-benzofuranyl)-3-methyl-
CAS No.:66202-99-1
Molecular Formula:C18H27N3O5
Molecular Weight:365.4241
Hs Code.:
DSSTox Substance ID:DTXSID40216380
Nikkaji Number:J87.659C
Wikidata:Q83092604
ChEMBL ID:CHEMBL46919

Synonyms:BRN 5147042;Urea, 1-(4,7-dimethoxy-6-(2-(diethylamino)ethoxy)-5-benzofuranyl)-3-methyl-;66202-99-1;N-(4,7-Dimethoxy-6-(2-(diethylamino)ethoxy)-5-benzofuranyl)-N'-methylurea;CHEMBL46919;DTXSID40216380;C18H27N3O5;LS-159885;1-[4,7-Dimethoxy-6-[2-(diethylamino)ethoxy]benzofuran-5-yl]-3-methylurea

Suppliers and Price of Urea, 1-(4,7-dimethoxy-6-(2-(diethylamino)ethoxy)-5-benzofuranyl)-3-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Urea, 1-(4,7-dimethoxy-6-(2-(diethylamino)ethoxy)-5-benzofuranyl)-3-methyl-

Chemical Property:

Vapor Pressure:2.25E-09mmHg at 25°C
Boiling Point:480°C at 760 mmHg
Flash Point:244.1°C
Density:1.178g/cm³
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:365.19507097
Heavy Atom Count:26
Complexity:435

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN(CC)CCOC1=C(C2=C(C=CO2)C(=C1NC(=O)NC)OC)OC

Technology Process of Urea, 1-(4,7-dimethoxy-6-(2-(diethylamino)ethoxy)-5-benzofuranyl)-3-methyl-

There total 5 articles about Urea, 1-(4,7-dimethoxy-6-(2-(diethylamino)ethoxy)-5-benzofuranyl)-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 66203-89-2
N-(4,7-dimethoxy-6-hydroxy-5-benzofuranyl)-N'-methylurea

: 100-35-6
2-(diethylamino)ethyl chloride

: 66202-99-1
1-[6-(2-Diethylamino-ethoxy)-4,7-dimethoxy-benzofuran-5-yl]-3-methyl-urea

Guidance literature:: With potassium carbonate; In acetonitrile; for 4h; Heating;
DOI:10.1021/jm00134a007

Reference yield:

: 52631-79-5
N-(4,7-dimethoxy-6-hydroxy-5-benzofuranyl)acetamide

: 66202-99-1
1-[6-(2-Diethylamino-ethoxy)-4,7-dimethoxy-benzofuran-5-yl]-3-methyl-urea

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / HCl / ethanol / 20 h / Heating

2: 89 percent / CHCl₃ / 2 h / Ambient temperature

3: 58 percent / K₂CO₃ / acetonitrile / 4 h / Heating

With hydrogenchloride; potassium carbonate; In ethanol; chloroform; acetonitrile;
DOI:10.1021/jm00134a007

Reference yield:

: 484-51-5
5-acetyl-6-hydroxy-4,7-dimethoxybenzofuran

: 66202-99-1
1-[6-(2-Diethylamino-ethoxy)-4,7-dimethoxy-benzofuran-5-yl]-3-methyl-urea

Guidance literature:: Multi-step reaction with 5 steps

1: 82 percent / hydroxylamine hydrochloride, conc. NaOH / ethanol; H₂O / 6 h / Heating

2: 75 percent / aq. AcOH, HCl(g) / 0.5 h / 90 °C

3: 90 percent / HCl / ethanol / 20 h / Heating

4: 89 percent / CHCl₃ / 2 h / Ambient temperature

5: 58 percent / K₂CO₃ / acetonitrile / 4 h / Heating

With hydrogenchloride; sodium hydroxide; hydroxylamine hydrochloride; potassium carbonate; acetic acid; In ethanol; chloroform; water; acetonitrile;
DOI:10.1021/jm00134a007