2-Bromo-n,n-diphenylacetamide

Base Information

• Chemical Name: 2-Bromo-n,n-diphenylacetamide
• CAS No.: 6335-34-8
• Molecular Formula: C14H12BrNO
• Molecular Weight: 290.159
• NSC Number: 29066
• DSSTox Substance ID: DTXSID00979484
• Nikkaji Number: J1.384.972B
• Wikidata: Q82965138
• Mol file: 6335-34-8.mol

Synonyms:2-bromo-n,n-diphenylacetamide;6335-34-8;2-bromo-N,N-di(phenyl)acetamide;NSC29066;N,N-diphenylbromoacetamide;SCHEMBL4227731;2-bromo-N,N-diphenyl acetamide;2-bromo-N,N-diphenyl-acetamide;N,N-Diphenyl-1-bromo-acetamide;DTXSID00979484;CIGSKJKGTWNQAX-UHFFFAOYSA-N;NSC-29066;2-Bromo-N,N-diphenylethanamide, 98%;CS-0454418

Chemical Property of 2-Bromo-n,n-diphenylacetamide

Chemical Property:

• Vapor Pressure: 1.95E-13mmHg at 25°C
• Boiling Point: 579.8°C at 760 mmHg
• Flash Point: 304.4°C
• Density: 1.51g/cm³
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 289.01023
• Heavy Atom Count: 17
• Complexity: 227

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)N(C2=CC=CC=C2)C(=O)CBr

Technology Process of 2-Bromo-n,n-diphenylacetamide

There total 3 articles about 2-Bromo-n,n-diphenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

diphenylamine (122-39-4) + 2-Bromoacetyl bromide (598-21-0) → 2-bromo-N,N-diphenylacetamide (6335-34-8)

Guidance literature:

With triethylamine; In toluene; for 4h; Reflux;

DOI:10.1021/acs.orglett.0c01523

Reference yield: 84.0%

2-bromoacetyl chloride (22118-09-8) + diphenylamine (122-39-4) → 2-bromo-N,N-diphenylacetamide (6335-34-8)

Guidance literature:

In benzene; for 4h; Heating;

Reference yield:

N,N-diphenylacetamide (519-87-9) → 2-bromo-N,N-diphenylacetamide (6335-34-8)

Guidance literature:

With copper(ll) bromide; In ethyl acetate; at 20 ℃;

DOI:10.1002/adsc.202101053

upstream raw materials:

2-bromoacetyl chloride

diphenylamine

2-Bromoacetyl bromide

N,N-diphenylacetamide

Downstream raw materials:

(2R,3S)-3-Phenyl-oxirane-2-carboxylic acid diphenylamide

1-phenyl-1,3-dihydro-indol-2-one

N,N-diphenylacetamide