Technology Process of 11-phenyl-5H-dibenzo[b,e][1,4]diazepine
There total 10 articles about 11-phenyl-5H-dibenzo[b,e][1,4]diazepine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tris-(dibenzylideneacetone)dipalladium(0); ammonia; 2'-(di-tert-butylphosphanyl)-N,N-dimethyl-[1,1'-biphenyl]-2-amine; sodium t-butanolate;
In
1,4-dioxane;
at 85 ℃;
for 2h;
Inert atmosphere;
Molecular sieve;
DOI:10.1021/ja206229y
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
methanol;
at 20 ℃;
for 0.0833333h;
Reagent/catalyst;
Temperature;
Time;
DOI:10.1016/j.cclet.2013.04.028
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tris-(dibenzylideneacetone)dipalladium(0); dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; potassium carbonate / tert-butyl alcohol / 5 h / 100 °C / Inert atmosphere
2: tris-(dibenzylideneacetone)dipalladium(0); ammonia; 2'-(di-tert-butylphosphanyl)-N,N-dimethyl-[1,1'-biphenyl]-2-amine; sodium t-butanolate / 1,4-dioxane / 2 h / 85 °C / Inert atmosphere; Molecular sieve
With
tris-(dibenzylideneacetone)dipalladium(0); dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; ammonia; potassium carbonate; 2'-(di-tert-butylphosphanyl)-N,N-dimethyl-[1,1'-biphenyl]-2-amine; sodium t-butanolate;
In
1,4-dioxane; tert-butyl alcohol;
DOI:10.1021/ja206229y
