7-<2,3-di-O-benzoyl-4-O-(2,3-di-O-benzoyl-4,6-O-benzylidene-β-D-glucopyranosyl)-6-O-triphenylmethyl-β-D-glucopyranosyl>theophylline

Base Information

• Chemical Name: 7-<2,3-di-O-benzoyl-4-O-(2,3-di-O-benzoyl-4,6-O-benzylidene-β-D-glucopyranosyl)-6-O-triphenylmethyl-β-D-glucopyranosyl>theophylline
• CAS No.: 80928-31-0
• Molecular Formula: C₇₃H₆₂N₄O₁₆
• Molecular Weight: 1251.31
• Mol file: 80928-31-0.mol

Synonyms:7-<2,3-di-O-benzoyl-4-O-(2,3-di-O-benzoyl-4,6-O-benzylidene-β-D-glucopyranosyl)-6-O-triphenylmethyl-β-D-glucopyranosyl>theophylline

Chemical Property of 7-<2,3-di-O-benzoyl-4-O-(2,3-di-O-benzoyl-4,6-O-benzylidene-β-D-glucopyranosyl)-6-O-triphenylmethyl-β-D-glucopyranosyl>theophylline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-<2,3-di-O-benzoyl-4-O-(2,3-di-O-benzoyl-4,6-O-benzylidene-β-D-glucopyranosyl)-6-O-triphenylmethyl-β-D-glucopyranosyl>theophylline

There total 8 articles about 7-<2,3-di-O-benzoyl-4-O-(2,3-di-O-benzoyl-4,6-O-benzylidene-β-D-glucopyranosyl)-6-O-triphenylmethyl-β-D-glucopyranosyl>theophylline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

benzoyl chloride (98-88-4) + 7-<4-O-(4,6-O-benzylidene-β-D-glucopyranosyl)-6-O-triphenylmethyl-β-D-glucopyranosyl>theophylline (80928-30-9) → 7-<2,3-di-O-benzoyl-4-O-(2,3-di-O-benzoyl-4,6-O-benzylidene-β-D-glucopyranosyl)-6-O-triphenylmethyl-β-D-glucopyranosyl>theophylline (80928-31-0)

Guidance literature:

With pyridine; 1) 20 h, 4 deg C, 2) 4 h, RT;

DOI:10.1016/S0008-6215(00)81908-4

Reference yield:

1,3-dimethyl-7-(trimethylsilyl)xanthine (62374-32-7) → 7-<2,3-di-O-benzoyl-4-O-(2,3-di-O-benzoyl-4,6-O-benzylidene-β-D-glucopyranosyl)-6-O-triphenylmethyl-β-D-glucopyranosyl>theophylline (80928-31-0)

Guidance literature:

Multi-step reaction with 5 steps

1: 90 percent / SnCl₄ / acetonitrile / 75 °C

2: 85 percent / NH₃ / methanol / Ambient temperature

3: 61 percent / ZnCl₂

4: 56 percent / pyridine / 18 h / 70 °C

5: 85 percent / pyridine / 1) 20 h, 4 deg C, 2) 4 h, RT

With pyridine; ammonia; tin(IV) chloride; zinc(II) chloride; In methanol; acetonitrile;

DOI:10.1016/S0008-6215(00)81908-4

Reference yield:

7-(hepta-O-acetyl-β-cellobiosyl)theophylline (80928-27-4) → 7-<2,3-di-O-benzoyl-4-O-(2,3-di-O-benzoyl-4,6-O-benzylidene-β-D-glucopyranosyl)-6-O-triphenylmethyl-β-D-glucopyranosyl>theophylline (80928-31-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 85 percent / NH₃ / methanol / Ambient temperature

2: 61 percent / ZnCl₂

3: 56 percent / pyridine / 18 h / 70 °C

4: 85 percent / pyridine / 1) 20 h, 4 deg C, 2) 4 h, RT

With pyridine; ammonia; zinc(II) chloride; In methanol;

DOI:10.1016/S0008-6215(00)81908-4

upstream raw materials:

benzoyl chloride

7-<4-O-(4,6-O-benzylidene-β-D-glucopyranosyl)-6-O-triphenylmethyl-β-D-glucopyranosyl>theophylline

trityl chloride

benzaldehyde

Downstream raw materials:

7-<2,3-di-O-benzoyl-6-bromo-6-deoxy-4-O-(2,3-di-O-benzoyl-6-bromo-6-deoxy-β-D-glucopyranosyl)-β-D-glucopyranosyl>theophylline

7-<2,3-di-O-benzoyl-6-deoxy-4-O-(2,3-di-O-benzoyl-6-deoxy-β-D-glucopyranosyl)-β-D-glucopyranosyl>theophylline

7-<2,3-di-O-benzoyl-4-O-(2,3-di-O-benzoyl-β-D-glucopyranosyl)-β-D-glucopyranosyl>theophylline