2-diazo-1-[5-(4-methoxybenzoyl)-2,3-dihydropyrrolizin-1-yl]ethanone

Base Information

• Chemical Name: 2-diazo-1-[5-(4-methoxybenzoyl)-2,3-dihydropyrrolizin-1-yl]ethanone
• CAS No.: 1093808-74-2
• Molecular Formula: C₁₇H₁₅N₃O₃
• Molecular Weight: 309.324
• Mol file: 1093808-74-2.mol

Synonyms:2-diazo-1-[5-(4-methoxybenzoyl)-2,3-dihydropyrrolizin-1-yl]ethanone

Chemical Property of 2-diazo-1-[5-(4-methoxybenzoyl)-2,3-dihydropyrrolizin-1-yl]ethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-diazo-1-[5-(4-methoxybenzoyl)-2,3-dihydropyrrolizin-1-yl]ethanone

There total 1 articles about 2-diazo-1-[5-(4-methoxybenzoyl)-2,3-dihydropyrrolizin-1-yl]ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + Anirolac (66635-85-6) → 2-diazo-1-[5-(4-methoxybenzoyl)-2,3-dihydropyrrolizin-1-yl]ethanone (1093808-74-2)

Guidance literature:

Anirolac; With N-Bromosuccinimide; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h;

diazomethane; In tetrahydrofuran; diethyl ether; at 20 ℃; Further stages.;

DOI:10.3184/030823407X268944

Reference yield: 45.0%

2-diazo-1-[5-(4-methoxybenzoyl)-2,3-dihydropyrrolizin-1-yl]ethanone (1093808-74-2) → 5-(4-methoxybenzoyl)-2,3-dihydropyrrolizin-1-one (1093808-76-4)

Guidance literature:

dirhodium tetraacetate; In dichloromethane; at 20 ℃; for 2h;

DOI:10.3184/030823407X268944

upstream raw materials:

diazomethane

Anirolac

Downstream raw materials:

5-(4-methoxybenzoyl)-2,3-dihydropyrrolizin-1-one