4,5-diiodobenzene-1,2-dicarbonitrile

Base Information

• Chemical Name: 4,5-diiodobenzene-1,2-dicarbonitrile
• CAS No.: 175883-98-4
• Molecular Formula: C₈H₂I₂N₂
• Molecular Weight: 379.926
• Mol file: 175883-98-4.mol

Synonyms:4,5-diiodobenzene-1,2-dicarbonitrile

Chemical Property of 4,5-diiodobenzene-1,2-dicarbonitrile

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5-diiodobenzene-1,2-dicarbonitrile

There total 7 articles about 4,5-diiodobenzene-1,2-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4,5-diiodophthaldiamide (175883-97-3) → 4,5-diiodobenzene-1,2-dicarbonitrile (175883-98-4)

Guidance literature:

With pyridine; trifluoroacetic anhydride; In 1,4-dioxane; at 0 - 25 ℃; for 12h;

DOI:10.1039/c4ob00901k

Reference yield: 80.0%

phthalimide (136918-14-4,85-41-6) → 4,5-diiodobenzene-1,2-dicarbonitrile (175883-98-4) + 3,4-diiodophthalonitrile

Guidance literature:

With pyridine; ammonium hydroxide; sulfuric acid; iodine; trifluoroacetic anhydride; Yield given. Multistep reaction; 1) 85-90 deg C, 24 h; 2) 50-60 deg C, 1.5 h; 3) dioxane, rt, overnight;

DOI:10.1021/jo9521662

Reference yield:

4,5-diiodophthalimide (68218-30-4) → 4,5-diiodobenzene-1,2-dicarbonitrile (175883-98-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / cc. aq. NH₃ / 1.5 h / 50 - 60 °C

2: 79 percent / trifluoroacetic anhydride, pyridine / dioxane / 0 - 5 °C

With pyridine; ammonium hydroxide; trifluoroacetic anhydride; In 1,4-dioxane;

DOI:10.1016/S1386-1425(97)00236-9

upstream raw materials:

phthalimide

4,5-diiodophthaldiamide

4,5-diiodophthalimide

o-xylene

Downstream raw materials:

4,5-bis(3,3-dimethyl-1-butynyl)phthalonitrile

4,5-di(1-pentynyl)phthalonitrile

4,5-di(1-heptynyl)phthalonitrile

4,5-di(1-octynyl)phthalonitrile