C₈H₉IN₂S

Base Information

• Chemical Name: C₈H₉IN₂S
• CAS No.: 763077-07-2
• Molecular Formula: C₈H₉IN₂S
• Molecular Weight: 292.143
• Mol file: 763077-07-2.mol

Synonyms:C₈H₉IN₂S

Chemical Property of C₈H₉IN₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₈H₉IN₂S

There total 1 articles about C₈H₉IN₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3-iodobenzylalcohol (57455-06-8) + thiourea (17356-08-0) → C8H9IN2S (763077-07-2)

Guidance literature:

With hydrogen bromide; In water; for 0.5h; Reflux;

DOI:10.1111/cbdd.12083

Reference yield: 80.0%

C8H9IN2S (763077-07-2) + chloroacetic acid (79-11-8) → (3-iodo-benzylsulfanyl)-acetic acid (867202-89-9)

Guidance literature:

C₈H₉IN₂S; With sodium hydroxide; In water; at 80 ℃; for 1h;

chloroacetic acid; for 2h; Reflux;

DOI:10.1111/cbdd.12083

Reference yield:

C8H9IN2S (763077-07-2) → 2-(3-Iodo-benzylsulfanyl)-acetamide (867202-91-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydroxide / 1 h / 80 °C

1.2: 2 h / Reflux

2.1: thionyl chloride / benzene / 3 h / Reflux

3.1: ammonium hydroxide / dichloromethane / 0.5 h / 0 - 20 °C

With ammonium hydroxide; thionyl chloride; sodium hydroxide; In dichloromethane; benzene;

DOI:10.1016/j.bmcl.2011.12.099

upstream raw materials:

3-iodobenzylalcohol

thiourea

Downstream raw materials:

2-(3-Iodo-phenylmethanesulfinyl)-acetamide

2-(3-Iodo-benzylsulfanyl)-acetamide

(3-iodo-benzylsulfanyl)-acetic acid