5-methyl-2-phenethyl-7-propyl-1⁽³⁾,4-dihydro-imidazo[5,1-f][1,2,4]triazine

Base Information

• Chemical Name: 5-methyl-2-phenethyl-7-propyl-1⁽³⁾,4-dihydro-imidazo[5,1-f][1,2,4]triazine
• CAS No.: 68282-18-8
• Molecular Formula: C₁₇H₂₂N₄
• Molecular Weight: 282.388
• Mol file: 68282-18-8.mol

Synonyms:5-methyl-2-phenethyl-7-propyl-1⁽³⁾,4-dihydro-imidazo[5,1-f][1,2,4]triazine

Chemical Property of 5-methyl-2-phenethyl-7-propyl-1⁽³⁾,4-dihydro-imidazo[5,1-f][1,2,4]triazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-methyl-2-phenethyl-7-propyl-1⁽³⁾,4-dihydro-imidazo[5,1-f][1,2,4]triazine

There total 8 articles about 5-methyl-2-phenethyl-7-propyl-1⁽³⁾,4-dihydro-imidazo[5,1-f][1,2,4]triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5-methyl-2-phenethyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (68282-02-0) → 5-methyl-2-phenethyl-7-propyl-1(3),4-dihydro-imidazo[5,1-f][1,2,4]triazine (68282-18-8)

Guidance literature:

With lithium aluminium tetrahydride; In 1,2-dimethoxyethane; for 2h; Heating;

Reference yield:

ethanol ethyl acetate (117204-61-2) + 5-methyl-2-phenethyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (68282-02-0) → 5-methyl-2-phenethyl-7-propyl-1(3),4-dihydro-imidazo[5,1-f][1,2,4]triazine (68282-18-8)

Guidance literature:

In 1,2-dimethoxyethane;

Reference yield:

3-phenethylpropanimidamide hydrochloride (24441-89-2) → 5-methyl-2-phenethyl-7-propyl-1(3),4-dihydro-imidazo[5,1-f][1,2,4]triazine (68282-18-8)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrazine hydrate / ethanol / 0.17 h / Ambient temperature

2: ethanol / 4 h / 70 °C

3: 74 percent / polyphosphoric acid / 0.75 h / 150 °C

4: 95 percent / LiAlH₄ / 1,2-dimethoxy-ethane / 2 h / Heating

With lithium aluminium tetrahydride; PPA; hydrazine hydrate; In 1,2-dimethoxyethane; ethanol;

upstream raw materials:

5-methyl-2-phenethyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one

3-phenethylpropanimidamide hydrochloride

C₉H₁₃N₃

ethyl 3-butyramido-2-oxobutyrate