1H-benzoimidazole-2-carboxylic acid {2-[4-(3,4-dimethoxy-benzoylamino)-phenyl]-2-methyl-propyl}-amide

Base Information

Chemical Name:1H-benzoimidazole-2-carboxylic acid {2-[4-(3,4-dimethoxy-benzoylamino)-phenyl]-2-methyl-propyl}-amide
CAS No.:1067191-59-6
Molecular Formula:C₂₇H₂₈N₄O₄
Molecular Weight:472.544
Hs Code.:

Synonyms:1H-benzoimidazole-2-carboxylic acid {2-[4-(3,4-dimethoxy-benzoylamino)-phenyl]-2-methyl-propyl}-amide

Suppliers and Price of 1H-benzoimidazole-2-carboxylic acid {2-[4-(3,4-dimethoxy-benzoylamino)-phenyl]-2-methyl-propyl}-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1H-benzoimidazole-2-carboxylic acid {2-[4-(3,4-dimethoxy-benzoylamino)-phenyl]-2-methyl-propyl}-amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-benzoimidazole-2-carboxylic acid {2-[4-(3,4-dimethoxy-benzoylamino)-phenyl]-2-methyl-propyl}-amide

There total 4 articles about 1H-benzoimidazole-2-carboxylic acid {2-[4-(3,4-dimethoxy-benzoylamino)-phenyl]-2-methyl-propyl}-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 2849-93-6
2-benzimidazolecarboxylic acid

: 1067192-41-9
N-[4-(2-amino-1,1-dimethyl-ethyl)-phenyl]-3,4-dimethoxy-benzamide

: 1067191-59-6
1H-benzoimidazole-2-carboxylic acid {2-[4-(3,4-dimethoxy-benzoylamino)-phenyl]-2-methyl-propyl}-amide

Guidance literature:: 2-benzimidazolecarboxylic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 ℃; for 3h;

N-[4-(2-amino-1,1-dimethyl-ethyl)-phenyl]-3,4-dimethoxy-benzamide; With triethylamine; In dichloromethane; at 0 - 20 ℃; for 16h;

Reference yield:

: 1067189-44-9
ADX₆₁₆₂₃

: 1067191-59-6
1H-benzoimidazole-2-carboxylic acid {2-[4-(3,4-dimethoxy-benzoylamino)-phenyl]-2-methyl-propyl}-amide

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogen / palladium 10% on activated carbon / methanol / 15 h / 20 °C / 2475.25 Torr

2.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 3 h / 0 °C

2.2: 16 h / 0 - 20 °C

With oxalyl dichloride; hydrogen; palladium 10% on activated carbon; N,N-dimethyl-formamide; In methanol; dichloromethane;

Reference yield:

: 115279-57-7
2-(4-aminophenyl)-2-methylpropionitrile

: 1067191-59-6
1H-benzoimidazole-2-carboxylic acid {2-[4-(3,4-dimethoxy-benzoylamino)-phenyl]-2-methyl-propyl}-amide

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane / 16 h / 20 °C

2.1: hydrogen / palladium 10% on activated carbon / methanol / 15 h / 20 °C / 2475.25 Torr

3.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 3 h / 0 °C

3.2: 16 h / 0 - 20 °C

With oxalyl dichloride; hydrogen; triethylamine; palladium 10% on activated carbon; N,N-dimethyl-formamide; In methanol; dichloromethane;