1-{4-chloro-5-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-(3,4,5-trimethoxybenzylthio)benzenesulfonyl}-3-hydroxyguanidine

Base Information

Chemical Name:1-{4-chloro-5-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-(3,4,5-trimethoxybenzylthio)benzenesulfonyl}-3-hydroxyguanidine
CAS No.:1398564-94-7
Molecular Formula:C₂₅H₂₃Cl₂N₅O₆S₃
Molecular Weight:656.592
Hs Code.:

Synonyms:1-{4-chloro-5-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-(3,4,5-trimethoxybenzylthio)benzenesulfonyl}-3-hydroxyguanidine

Suppliers and Price of 1-{4-chloro-5-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-(3,4,5-trimethoxybenzylthio)benzenesulfonyl}-3-hydroxyguanidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-{4-chloro-5-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-(3,4,5-trimethoxybenzylthio)benzenesulfonyl}-3-hydroxyguanidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-{4-chloro-5-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-(3,4,5-trimethoxybenzylthio)benzenesulfonyl}-3-hydroxyguanidine

There total 3 articles about 1-{4-chloro-5-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-(3,4,5-trimethoxybenzylthio)benzenesulfonyl}-3-hydroxyguanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: N-{4-chloro-2-(3,4,5-trimethoxybenzylthio)-5-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]benzenesulfonyl}cyanamide potassium salt

: 1398564-94-7
1-{4-chloro-5-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-(3,4,5-trimethoxybenzylthio)benzenesulfonyl}-3-hydroxyguanidine

Guidance literature:: With hydroxylamine hydrochloride; In acetonitrile; at 83 ℃;
DOI:10.1016/j.ejmech.2012.07.042

Reference yield:

: 1318988-81-6
6-chloro-7-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-3-methylthio-1,1-dioxo-1,4,2-benzodithiazine

: 1398564-94-7
1-{4-chloro-5-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-(3,4,5-trimethoxybenzylthio)benzenesulfonyl}-3-hydroxyguanidine

Guidance literature:: Multi-step reaction with 3 steps

1: ammonium hydroxide / methanol / 20 °C

2: potassium carbonate / tetrahydrofuran / 65 °C

3: hydroxylamine hydrochloride / acetonitrile / 83 °C

With ammonium hydroxide; hydroxylamine hydrochloride; potassium carbonate; In tetrahydrofuran; methanol; acetonitrile;
DOI:10.1016/j.ejmech.2012.07.042

Reference yield:

: 1318988-89-4
3-amino-6-chloro-7-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-1,1-dioxo-1,4,2-benzodithiazine

: 3840-30-0
5-(chloromethyl)-1,2,3-trimethoxybenzene

: 1398564-94-7
1-{4-chloro-5-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-(3,4,5-trimethoxybenzylthio)benzenesulfonyl}-3-hydroxyguanidine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / tetrahydrofuran / 65 °C

2: hydroxylamine hydrochloride / acetonitrile / 83 °C

With hydroxylamine hydrochloride; potassium carbonate; In tetrahydrofuran; acetonitrile;
DOI:10.1016/j.ejmech.2012.07.042