benzyl 2,6,6'-tri-O-benzyl-2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside

Base Information

• Chemical Name: benzyl 2,6,6'-tri-O-benzyl-2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside
• CAS No.: 117475-20-4
• Molecular Formula: C₄₅H₅₃ClO₁₁
• Molecular Weight: 805.362
• Mol file: 117475-20-4.mol

Synonyms:benzyl 2,6,6'-tri-O-benzyl-2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside

Chemical Property of benzyl 2,6,6'-tri-O-benzyl-2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 2,6,6'-tri-O-benzyl-2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside

There total 1 articles about benzyl 2,6,6'-tri-O-benzyl-2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

benzyl 2,6,6'-tri-O-benzyl-3',4'-O-isopropylidene-β-lactoside (105186-56-9) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → benzyl 2,6,6'-tri-O-benzyl-2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside (117475-20-4) + benzyl 2,6,6'-tri-O-benzyl-3-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside (117475-21-5) + benzyl 2,6,6'-tri-O-benzyl-3,2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside (117475-22-6)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In water; at 50 ℃; for 6h;

DOI:10.1016/S0040-4020(01)85932-9

Reference yield: 80.0%

acetic anhydride (108-24-7) + benzyl 2,6,6'-tri-O-benzyl-2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside (117475-20-4) → benzyl 3-O-acetyl-2,6,6'-tri-O-benzyl-2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside (117475-23-7)

Guidance literature:

In pyridine;

DOI:10.1016/S0040-4020(01)85932-9

Reference yield: 35.0%

benzyl 2,6,6'-tri-O-benzyl-2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside (117475-20-4) + benzyl 2,6,6'-tri-O-benzyl-3-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside (117475-21-5) → C90H104O22 (117475-18-0) + C90H104O22 (117475-17-9)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 70 ℃; for 21h;

DOI:10.1016/S0040-4020(01)85932-9

upstream raw materials:

benzyl 2,6,6'-tri-O-benzyl-3',4'-O-isopropylidene-β-lactoside

1,2-dichloro-ethane

Downstream raw materials:

benzyl 3-O-acetyl-2,6,6'-tri-O-benzyl-2'-O-(2-chloroethyl)-3',4'-O-isopropylidene β-lactoside

C₉₀H₁₀₄O₂₂

C₉₀H₁₀₄O₂₂