1,2-Dichloroethane

Base Information

• Chemical Name: 1,2-Dichloroethane
• CAS No.: 107-06-2
• Deprecated CAS: 52399-93-6
• Molecular Formula: C2H4Cl2
• Molecular Weight: 98.9598
• Hs Code.: 2903150000
• European Community (EC) Number: 203-458-1
• ICSC Number: 0250
• UN Number: 1184
• UNII: 55163IJI47
• DSSTox Substance ID: DTXSID6020438
• Nikkaji Number: J4.049E
• Wikipedia: 1,2-Dichloroethane,Ethylene dichloride
• Wikidata: Q161480
• NCI Thesaurus Code: C44383
• Metabolomics Workbench ID: 43912
• ChEMBL ID: CHEMBL16370
• Mol file: 107-06-2.mol

Synonyms:1,2-dichloroethane;ethylene dichloride;ethylene dichloride, 14C-labeled;ethylene dichloride, 14C2-labeled;ethylene dichloride, 36Cl-labeled;ethylene dichloride, 38Cl-labeled;ethylene dichloride, ion (1+)

Chemical Property of 1,2-Dichloroethane

Chemical Property:

• Appearance/Colour: clear liquid
• Vapor Pressure: 83.9mmHg at 25°C
• Melting Point: -35 °C
• Refractive Index: 1.4448
• Boiling Point: 83.5 °C at 760 mmHg
• Flash Point: 15.6 °C
• PSA: 0.00000
• Density: 1.173 g/cm³
• LogP: 1.46400
• Water Solubility.: 8.7 g/L (20℃)
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 97.9690055
• Heavy Atom Count: 4
• Complexity: 6
• Transport DOT Label: Flammable Liquid Poison

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F,T
• Hazard Codes: F:Flammable;;
• Statements: R11:; R22:; R36/37/38:; R45:
• Safety Statements: S45:; S53:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Chlorinated Aliphatics
• Canonical SMILES: C(CCl)Cl
• Inhalation Risk: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: The vapour is irritating to the eyes, skin and respiratory tract. Inhalation may cause lung oedema. The substance may cause effects on the kidneys and liver. This may result in impaired functions, liver damage and kidney damage. Exposure at high concentrations could cause lowering of consciousness and death. The effects may be delayed.
• Effects of Long Term Exposure: Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the liver and kidneys, resulting in impaired functions. This substance is possibly carcinogenic to humans.

Technology Process of 1,2-Dichloroethane

There total 217 articles about 1,2-Dichloroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.6%

dichloromethane (75-09-2) + aniline (62-53-3) → N-methylenebenzenamine (100-62-9) + methylene chloride (74-87-3) + 1,2-dichloro-ethane (107-06-2,52399-93-6) + Azobenzene (1227476-15-4) + N-phenylphenylene-1,4-diamine (101-54-2) + N-phenyl-1,2-benzenediamine (534-85-0)

Guidance literature:

at 15 ℃; for 24h; Product distribution; Mechanism; Irradiation;

Reference yield:

benzyl chloride (100-44-7) + ethylene dibromide (106-93-4) → benzyl bromide (100-39-0) + 1,2-dichloro-ethane (107-06-2,52399-93-6) + 1-Bromo-2-chloroethane (107-04-0)

Guidance literature:

at 150 ℃; under 760.051 Torr; Gas phase;

DOI:10.1039/c7ra12579h

Reference yield:

ClCH2Co(COOCH3)(CO)3(1-) (106865-88-7) → dimethyl cis-but-2-ene-1,4-dioate (624-48-6) + methyl chloroacetate (96-34-4) + 1,2-dichloro-ethane (107-06-2,52399-93-6) + 1,3-Dichloroacetone (534-07-6) + Dimethyl succinate (106-65-0)

Guidance literature:

In tetrahydrofuran; byproducts: Co(CO)4(1-); soln. of the Co-complex was gradually warmed from -40°C to room temp. in 2 h under Ar atmosphere; reaction mixt. was analyzed by IR spectroscopy and gas chromy.; GC yield of dimethyl malonate 9.5% (from the two stages);

DOI:10.1021/om00147a028

upstream raw materials:

oxirane

Methanesulfenyl chloride

methylene chloride

chloroethyl chlorosulfate

Downstream raw materials:

tetra-O-benzoyl-β-D-ribopyranose

1-cyano-1-phenylcyclopropane

azulen-1-yl-(2,4-dinitro-phenyl)-sulfide

3-thiapentan-1,5-dithiol

Refernces

• 1、 Misochko, E. Ya.,Wight, C. A.,Vetoshkin, E. V.,Benderskii, V. A.. "Tunneling dynamics and spatial correlations of long chain growth in solid-state photochlorination of ethylene at low temperatures". . p. 648 - 662. Retrieved 1993.
• 2、 Kaiser,Wallington. "Kinetics of the reactions of chlorine atoms with C2H4 (k1) and C2H2 (k2): A determination of ΔHf,298° for C2H3". . p. 4111 - 4119. Retrieved 1996.
• 3、 Dolci, Sara,Marchetti, Fabio,Pampaloni, Guido,Zacchini, Stefano. "A systematic study on the activation of simple polyethers by MoCl 5 and WCl6". . p. 5367 - 5376. Retrieved 2010.
• 4、 Williams. "-". . p. 318. Retrieved 1947.
• 5、 Wagner, George W.,Maciver, Brian K.,Rohrbaugh, Dennis K.,Yang, Yu-Chu. "Thermal degradation of bis (2-chloroethyl) sulfide (mustard gas)". . p. 65 - 76. Retrieved 1999.
• 6、 Chambers, Alan,Rodriguez, Nelly M.,Baker, R. Terry K.. "Influence of Silver Addition on the Catalytic Behavior of Cobalt". . p. 4229 - 4236. Retrieved 1996.
• 7、 Olah et al.. "-". . p. 7686,7688. Retrieved 1973.
• 8、 Marino,Brown. "-". . p. 5929,5931, 5932. Retrieved 1959.
• 9、 Vasil'ev, Yu. B.,German, L. S.,Grinberg, V. A.,Kazarinov, V. E.,Mysov, E. I.,Skundin, A. M.. "TELOMERIZATION OF ETHYLENE BY ANODICALLY GENERATED CHLORINE". . p. 523 - 525. Retrieved 1983.
• 10、 Mowry,Ringwald. "-". . p. 4439 Anm. 1. Retrieved 1950.