8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-ethyl-6-phenyl-

Base Information

Chemical Name:8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-ethyl-6-phenyl-
CAS No.:103357-77-3
Molecular Formula:C₁₅H₁₁N₃OS₂
Molecular Weight:313.404
Hs Code.:
ChEMBL ID:CHEMBL2088245
DSSTox Substance ID:DTXSID90145797

Synonyms:BRN 5600612;8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-ethyl-6-phenyl-;103357-77-3;2-Ethyl-6-phenyl-8H-(1,3,4)thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one;CHEMBL2088245;DTXSID90145797

Suppliers and Price of 8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-ethyl-6-phenyl-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-ethyl-6-phenyl-

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:313.03435433
Heavy Atom Count:21
Complexity:513

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=NN2C(=O)C3=C(N=C2S1)SC(=C3)C4=CC=CC=C4

Technology Process of 8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-ethyl-6-phenyl-

There total 4 articles about 8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-ethyl-6-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 71859-81-9
2-alogeno-1,3,4-tiadiazolo-5-etili

: 4815-34-3
ethyl 2-amino-5-phenylthiophene-3-carboxylate

: 103357-77-3
2-ethyl-6-phenyl-8H-<1,3,4>thiadiazolo<3,2-a>thieno<2,3-d>pyrimidin-8-one

Guidance literature:: at 160 ℃;

Reference yield: 47.0%

: 802294-64-0,79-09-4
propionic acid

: 155054-32-3
2,3-dihydro-3-amino-6-phenyl-2-thioxothieno<2,3-d>pyrimidin-4(1H)-one

: 103357-77-3
2-ethyl-6-phenyl-8H-<1,3,4>thiadiazolo<3,2-a>thieno<2,3-d>pyrimidin-8-one

Guidance literature:: With methanesulfonic acid; phosphorus pentoxide; at 80 ℃; for 9h;

Reference yield:

: 85716-86-5
2-isothiocyanato-5-phenyl-3-thiophenecarboxylic acid ethyl ester

: 103357-77-3
2-ethyl-6-phenyl-8H-<1,3,4>thiadiazolo<3,2-a>thieno<2,3-d>pyrimidin-8-one

Guidance literature:: Multi-step reaction with 3 steps

1: 40 percent / NH₂NH₂*H₂O / CH₂Cl₂ / 2 h / Ambient temperature

2: 1.) KOH, 2.) 37percent HCl / ethanol / 0.5 h / Heating

3: 47 percent / CH₃SO₃H, P₂O₅ / 9 h / 80 °C

With hydrogenchloride; potassium hydroxide; methanesulfonic acid; phosphorus pentoxide; hydrazine hydrate; In ethanol; dichloromethane;