2H-Isoindole-2-heptanamide, 1,3-dihydro-1,3-dioxo-N-(3-ethyl-1-phenyl-1H-indol-2-yl)-

Base Information

Chemical Name:2H-Isoindole-2-heptanamide, 1,3-dihydro-1,3-dioxo-N-(3-ethyl-1-phenyl-1H-indol-2-yl)-
CAS No.:138349-47-0
Molecular Formula:C₃₁H₃₁N₃O₃
Molecular Weight:493.605
Hs Code.:
DSSTox Substance ID:DTXSID20160630
Nikkaji Number:J440.282K
Wikidata:Q83028989
Mol file:138349-47-0.mol

Synonyms:BRN 5463305;2H-Isoindole-2-heptanamide, 1,3-dihydro-1,3-dioxo-N-(3-ethyl-1-phenyl-1H-indol-2-yl)-;1,3-Dihydro-1,3-dioxo-N-(3-ethyl-1-phenyl-1H-indol-2-yl)-2H-isoindole-2-heptanamide;138349-47-0;DTXSID20160630;C31H31N3O3;C31-H31-N3-O3;LS-84672;N-(1-Phenyl-3-ethyl-1H-indol-2-yl)-7-(1,3-dioxoisoindolin-2-yl)heptanamide

Suppliers and Price of 2H-Isoindole-2-heptanamide, 1,3-dihydro-1,3-dioxo-N-(3-ethyl-1-phenyl-1H-indol-2-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2H-Isoindole-2-heptanamide, 1,3-dihydro-1,3-dioxo-N-(3-ethyl-1-phenyl-1H-indol-2-yl)-

Chemical Property:

Vapor Pressure:1.52E-16mmHg at 25°C
Boiling Point:645.3°Cat760mmHg
Flash Point:344.1°C
Density:1.21g/cm³
XLogP3:6.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:10
Exact Mass:493.23654186
Heavy Atom Count:37
Complexity:786

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C(N(C2=CC=CC=C21)C3=CC=CC=C3)NC(=O)CCCCCCN4C(=O)C5=CC=CC=C5C4=O

Technology Process of 2H-Isoindole-2-heptanamide, 1,3-dihydro-1,3-dioxo-N-(3-ethyl-1-phenyl-1H-indol-2-yl)-

There total 2 articles about 2H-Isoindole-2-heptanamide, 1,3-dihydro-1,3-dioxo-N-(3-ethyl-1-phenyl-1H-indol-2-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 69014-82-0
7-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-heptanoyl chloride

: 138349-59-4
2-amino-1-phenyl-3-ethylindole hydrochloride

: 138349-47-0
7-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-heptanoic acid (3-ethyl-1-phenyl-1H-indol-2-yl)-amide

Guidance literature:: With triethylamine; In dichloromethane; at 5 ℃; Yield given;
DOI:10.1007/BF00767254

Reference yield:

: 1154-46-7
7-(1,3-dioxoisoindolin-2-yl)heptanoic acid

: 138349-47-0
7-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-heptanoic acid (3-ethyl-1-phenyl-1H-indol-2-yl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂, DMF / CH₂Cl₂ / 2 h / Heating

2: Et₃N / CH₂Cl₂ / 5 °C

With thionyl chloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1007/BF00767254