4,4'-bis[2-(N-{2-[4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclodecan-1-yl]acetyl}-N-phenethyl)aminoethoxy]diphenylmethane

Base Information

• Chemical Name: 4,4'-bis[2-(N-{2-[4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclodecan-1-yl]acetyl}-N-phenethyl)aminoethoxy]diphenylmethane
• CAS No.: 1173758-78-5
• Molecular Formula: C₈₃H₁₂₆N₁₀O₁₆
• Molecular Weight: 1519.97
• Mol file: 1173758-78-5.mol

Synonyms:4,4'-bis[2-(N-{2-[4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclodecan-1-yl]acetyl}-N-phenethyl)aminoethoxy]diphenylmethane

Chemical Property of 4,4'-bis[2-(N-{2-[4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclodecan-1-yl]acetyl}-N-phenethyl)aminoethoxy]diphenylmethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4'-bis[2-(N-{2-[4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclodecan-1-yl]acetyl}-N-phenethyl)aminoethoxy]diphenylmethane

There total 1 articles about 4,4'-bis[2-(N-{2-[4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclodecan-1-yl]acetyl}-N-phenethyl)aminoethoxy]diphenylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

4,4'-{bis[2-(N-phenethyl)]aminoethoxy}diphenylmethane (1173758-67-2) + 2-(4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid (247193-74-4) → 4,4'-bis[2-(N-{2-[4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclodecan-1-yl]acetyl}-N-phenethyl)aminoethoxy]diphenylmethane (1173758-78-5)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1248/cpb.57.95

Reference yield: 100.0%

4,4'-bis[2-(N-{2-[4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclodecan-1-yl]acetyl}-N-phenethyl)aminoethoxy]diphenylmethane (1173758-78-5) → ACPCn octahydrochloride

Guidance literature:

With hydrogenchloride; water; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1248/cpb.57.95

upstream raw materials:

4,4'-{bis[2-(N-phenethyl)]aminoethoxy}diphenylmethane

2-(4,7,10-tris(tert-butoxycarbonyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid