N₄-[(1S)-1-(4-aminophenyl)ethyl]-N₂,N₂,7-trimethylquinazoline-2,4-diamine

Base Information

Chemical Name:N₄-[(1S)-1-(4-aminophenyl)ethyl]-N₂,N₂,7-trimethylquinazoline-2,4-diamine
CAS No.:1039736-60-1
Molecular Formula:C₁₉H₂₃N₅
Molecular Weight:321.425
Hs Code.:

N<sub>4</sub>-[(1S)-1-(4-aminophenyl)ethyl]-N<sub>2</sub>,N<sub>2</sub>,7-trimethylquinazoline-2,4-diamine

Synonyms:N₄-[(1S)-1-(4-aminophenyl)ethyl]-N₂,N₂,7-trimethylquinazoline-2,4-diamine

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Chemical Property of N₄-[(1S)-1-(4-aminophenyl)ethyl]-N₂,N₂,7-trimethylquinazoline-2,4-diamine

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Technology Process of N₄-[(1S)-1-(4-aminophenyl)ethyl]-N₂,N₂,7-trimethylquinazoline-2,4-diamine

There total 4 articles about N₄-[(1S)-1-(4-aminophenyl)ethyl]-N₂,N₂,7-trimethylquinazoline-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1039736-59-8
N₂,N₂,7-trimethyl-N₄-[(1S)-1-(4-nitrophenyl)ethyl]quinazoline-2,4-diamine

: 1039736-60-1
N₄-[(1S)-1-(4-aminophenyl)ethyl]-N₂,N₂,7-trimethylquinazoline-2,4-diamine

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; methanol;

Reference yield:

: 25171-19-1
7-methyl-2,4-dichloroquinazoline

: 1039736-60-1
N₄-[(1S)-1-(4-aminophenyl)ethyl]-N₂,N₂,7-trimethylquinazoline-2,4-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / tetrahydrofuran / 0 - 20 °C

2: tetrahydrofuran; isopropyl alcohol / Heating / reflux

3: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; methanol

With hydrogen; triethylamine; palladium 10% on activated carbon; In tetrahydrofuran; methanol; isopropyl alcohol;

Reference yield:

: 1039736-58-7
2-chloro-7-methyl-N-[(1S)-1-(4-nitrophenyl)ethyl]quinazolin-4-amine

: 1039736-60-1
N₄-[(1S)-1-(4-aminophenyl)ethyl]-N₂,N₂,7-trimethylquinazoline-2,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; isopropyl alcohol / Heating / reflux

2: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; methanol

With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; methanol; isopropyl alcohol;