D-Glucitol, 4-O-beta-D-galactopyranosyl-

Base Information Edit

Chemical Name:D-Glucitol, 4-O-beta-D-galactopyranosyl-
CAS No.:585-86-4
Molecular Formula:C₁₂H₂₄O₁₁
Molecular Weight:344.316
Hs Code.:
NSC Number:231900,231323
Mol file:585-86-4.mol

Synonyms:D-Glucitol, 4-O-.beta.-D-galactopyranosyl-;D-Lactitol (monohydrate);D-Glucopyranosyl-D-glucitol;NSC231323;D-Glucitol, 4-O-alpha-D-glucopyranosyl-;Glucitol, 4-O-alpha-D-glucopyranosyl-, D-;Maltitol (6CI,7CI);SCHEMBL433320;VQHSOMBJVWLPSR-UHFFFAOYSA-N;HMS3369N22;HMS3373A21;NSC231900;AKOS015900961;NSC-231900;SB48265;NCGC00181105-01;LS-71389;FT-0619324;FT-0627647;E80669;F531BE50-2A62-450A-A1A3-A106FA08AC06

Suppliers and Price of D-Glucitol, 4-O-beta-D-galactopyranosyl-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Lactitol anhydrous
1kg
$ 340.00

TRC
Lactitol
1g
$ 110.00

TRC
Lactitol
5g
$ 150.00

Sigma-Aldrich
Lactitol United States Pharmacopeia (USP) Reference Standard
500 mg
$ 414.00

Medical Isotopes, Inc.
Lactitolanhydrous
2 g
$ 580.00

Biosynth Carbosynth
Lactitol anhydrous
1 g
$ 145.00

Biosynth Carbosynth
Lactitol anhydrous
500 mg
$ 75.00

Biosynth Carbosynth
Lactitol anhydrous
5 g
$ 195.00

Biosynth Carbosynth
Lactitol anhydrous
2 g
$ 175.00

Biosynth Carbosynth
Lactitol anhydrous
10 g
$ 325.00

Total 92 raw suppliers

Chemical Property of D-Glucitol, 4-O-beta-D-galactopyranosyl- Edit

Chemical Property:

Appearance/Colour:White crystalline powder
Vapor Pressure:9.8E-29mmHg at 25°C
Melting Point:98-102oC
Refractive Index:1.634
Boiling Point:788.5 °C at 760 mmHg
PKA:12.84±0.70(Predicted)
Flash Point:430.7 °C
PSA：200.53000
Density:1.69 g/cm³
LogP:-5.76120
Storage Temp.:Hygroscopic, Refrigerator, under inert atmosphere
Solubility.:Slightly soluble in ethanol (95%) and ether. Soluble 1 in 1.75 of water at 20°C; 1 in 1.61 at 30°C; 1 in 1.49 at 40°C; 1 in 1.39 at 50°C.
XLogP3:-5.2
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:8
Exact Mass:344.13186158
Heavy Atom Count:23
Complexity:343

Purity/Quality:

95%~102% ^*data from raw suppliers

Lactitol anhydrous ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C(C1C(C(C(C(O1)OC(C(CO)O)C(C(CO)O)O)O)O)O)O
Description Lactitol (4-o-(|3-D-Galactopyranosyl)-D-glucitol) is a disaccharide sugar alcohol derived from lactose by reduction of its glucose moiety. Lactitol has not been found in nature. It is about 0.4 times as sweet as sucrose.In vitro studies with galactosidase-containing enzyme preparations have demonstrated that lactitol is hydrolyzed only very slowly. In incubations with human intestinal biopsies, it has been shown that the human intestinal mucosa does not exhibit any significant dis accharidase activity with lactitol as a substrate. The hydrolytic activities towards lactitol and isomalt were only 1.3% of those towards lactose and isomaltulose, respectively. Corresponding exper iments with intestinal preparations of germ-free pigs and convention ally kept minipigs gave similar results. These observations indicate that lactitol is the most slowly digested disaccharide sugar alcohol. However, in vitro investigations with intestinal enzyme prepara tions provide only relative figures on hydrolysis rates. Experiments with humans and 14C-labeled lactitol during jejunal perfusion indi cate that lactitol is virtually not assimilated by the human small intestine. After passage through the small intestine, ingested lac titol reaches the bacterially colonized segments of the gut where intensive fermentation takes place. Short-chain fatty acids (acetate, propionate, butyrate) are the major fermentation end products which are subsequently further metabolized by the host.Lactitol is slowly fermented in growing cultures by some strepto cocci, actinomyces and lactobacilli. When fed at 25% of the diet to rats that had been inoculated with Streptococcus mutans, lactitol was about equally as cariogenic as sorbitol and significantly less cariogenic than sucrose. Test candies and chocolates sweetened by lactitol are hypoacidogenic in humans tested by plaque pH telemetry. Boiled sweets made with 100% lactitol are rough in texture owing to crystallization, and caused some gastrointestinal upsets in human volunteers. Since lactitol has only one-third the sweetness of sucrose, sweets need an additional sweetening agent for palatability.
Uses Lactitol is listed as an excipient in some prescription drugs, such as Adderall. Lactitol is a sugar alcohol used as a replacement bulk sweetener for low calorie foods. It is also used medically as a laxative.

Technology Process of D-Glucitol, 4-O-beta-D-galactopyranosyl-

There total 16 articles about D-Glucitol, 4-O-beta-D-galactopyranosyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.9%