2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one

Base Information

• Chemical Name: 2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one
• CAS No.: 942-41-6
• Molecular Formula: C7H11 N5 O
• Molecular Weight: 181.197
• Hs Code.: 2933990090
• Mol file: 942-41-6.mol

Synonyms:4(1H)-Pteridinone,2-amino-5,6,7,8-tetrahydro-6-methyl- (9CI); 4-Pteridinol,2-amino-5,6,7,8-tetrahydro-6-methyl- (6CI,7CI,8CI);(6RS)-Methyltetrahydropterin;2-Amino-4-hydroxy-6-methyl-5,6,7,8-tetrahydropteridine;2-Amino-4-hydroxy-6-methyl-5,6,7,8-tetrahydropterin;2-Amino-4-hydroxy-6-methyltetrahydropteridine;2-Amino-4-hydroxy-6-methyltetrahydropterin; 5,6,7,8-Tetrahydro-6-methylpterin;6-Methyl-5,6,7,8-tetrahydropterin; 6-Methyltetrahydropterin;DL-6-Methyl-5,6,7,8-tetrahydropterin

Chemical Property of 2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one

Chemical Property:

• Vapor Pressure: 4.51E-05mmHg at 25°C
• Boiling Point: 350.1°Cat760mmHg
• Flash Point: 165.5°C
• PSA: 95.83000
• Density: 1.8g/cm³
• LogP: 0.43520

Purity/Quality:

99% ^*data from raw suppliers

2-amino-5,6,7,8-tetrahydro-6-methyl-4(3H)-Pteridinone 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one

There total 3 articles about 2-amino-6-methyl-5,6,7,8-tetrahydro-1H-pteridin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

2-amino-6-methylpteridin-4(1H)-one (708-75-8) + benzenesulfonic acid (98-11-3) → 6-methyl-5,6,7,8-tetrahydrobopterin (942-41-6)

Guidance literature:

bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In tetrahydrofuran; methanol;

2-amino-6-methylpteridin-4(1H)-one; benzenesulfonic acid; With hydrogen; In methanl; at 70 ℃; for 15h; under 60006 Torr; Product distribution / selectivity;

Reference yield:

2-amino-6-methylpteridin-4(1H)-one (708-75-8) → 6-methyl-5,6,7,8-tetrahydrobopterin (942-41-6)

Guidance literature:

With sodium hydroxide; Hydrogenation;

Reference yield:

→ 6-methyl-5,6,7,8-tetrahydrobopterin (942-41-6)

Guidance literature:

Verb.II/H2(Pt) in CF3COOH (Nebenprod.III);

DOI:10.1002/hlca.19740570844

upstream raw materials:

2-amino-6-methylpteridin-4(1H)-one

benzenesulfonic acid

Downstream raw materials:

6-Methyl-7,8-dihydropterin

6-methyl-5,6,7,8-tetrahydropterin

benzene-1,2-diol