tert-butyl N-{4-[5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl]cyclohexyl}-L-leucinate

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Chemical Name:tert-butyl N-{4-[5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl]cyclohexyl}-L-leucinate
CAS No.:1024949-55-0
Molecular Formula:C₃₇H₄₂Cl₃FN₂O₃
Molecular Weight:688.109
Hs Code.:

Synonyms:tert-butyl N-{4-[5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl]cyclohexyl}-L-leucinate

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Chemical Property of tert-butyl N-{4-[5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl]cyclohexyl}-L-leucinate

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Technology Process of tert-butyl N-{4-[5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl]cyclohexyl}-L-leucinate

There total 1 articles about tert-butyl N-{4-[5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl]cyclohexyl}-L-leucinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 1024500-43-3
5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-(4-oxocyclohexyl)-3,4-dihydroquinolin-2(1H)-one

: 2748-02-9,13081-32-8
L-leucine tert-butyl ester hydrochloride

: 1024949-55-0
tert-butyl N-{4-[5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl]cyclohexyl}-L-leucinate

Guidance literature:: 5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-(4-oxocyclohexyl)-3,4-dihydroquinolin-2(1H)-one; L-leucine tert-butyl ester hydrochloride; With triethylamine; In 1,2-dichloro-ethane; for 0.333333h;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; for 4h;

With water; sodium hydrogencarbonate; In dichloromethane; 1,2-dichloro-ethane;