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Technology Process of Gossypol

Gossypol

Base Information
  • Chemical Name:Gossypol
  • CAS No.:90141-22-3
  • Deprecated CAS:732279-01-5,40112-23-0,123732-23-0,40112-23-0
  • Molecular Formula:C30H30 O8
  • Molecular Weight:518.5544
  • Hs Code.:
  • European Community (EC) Number:636-899-7
  • NSC Number:728875,726190,624336,56817
  • UNII:8DY2X8LXW4,XNA7DR63CQ,KAV15B369O
  • DSSTox Substance ID:DTXSID5023110
  • Nikkaji Number:J126.059F,J2.536.108C,J2.536.109A,J858.559H,J21.393D
  • Wikipedia:Gossypol
  • Wikidata:Q411882
  • NCI Thesaurus Code:C529
  • Pharos Ligand ID:729J55RF7KWH
  • Metabolomics Workbench ID:28312
  • ChEMBL ID:CHEMBL51483
Gossypol

Synonyms:Dipotassium Salt, Gossypol;Gossypol;Gossypol Dipotassium Salt;Gossypol Sodium Salt;Gossypol, (+)-Isomer;Gossypol, (+-)-Isomer;Gossypol, (-)-Isomer;Sodium Salt, Gossypol

Suppliers and Price of Gossypol
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • AT101
  • 5mg
  • $ 130.00
  • Sigma-Aldrich
  • AT101 ≥98% (HPLC)
  • 5mg
  • $ 103.00
  • Sigma-Aldrich
  • AT101 ≥98% (HPLC)
  • 25mg
  • $ 407.00
  • CSNpharm
  • AT-101
  • 50mg
  • $ 408.00
  • BroadPharm
  • AT101 98%
  • 50 MG
  • $ 300.00
  • BroadPharm
  • AT101 98%
  • 25 MG
  • $ 200.00
  • AvaChem
  • (R)-(-)-Gossypol
  • 100mg
  • $ 890.00
  • AvaChem
  • (R)-(-)-Gossypol
  • 10mg
  • $ 115.00
  • AvaChem
  • (R)-(-)-Gossypol
  • 25mg
  • $ 290.00
  • ApexBio Technology
  • AT-101
  • 50mg
  • $ 330.00
Total 33 raw suppliers
Chemical Property of Gossypol
Chemical Property:
  • Melting Point:166-167℃ 
  • Boiling Point:707.9 ºCat 760 mmHg 
  • PKA:7.15±0.50(Predicted) 
  • Flash Point:395.9ºC 
  • PSA：155.52000 
  • Density:1.403 g/cm3 
  • LogP:6.38220 
  • Storage Temp.:Store at -20°C 
  • Solubility.:DMSO: soluble15mg/mL, clear 
  • XLogP3:6.9
  • Hydrogen Bond Donor Count:6
  • Hydrogen Bond Acceptor Count:8
  • Rotatable Bond Count:5
  • Exact Mass:518.19406791
  • Heavy Atom Count:38
  • Complexity:780
Purity/Quality:

99%, *data from raw suppliers

AT101 *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1=CC2=C(C(=C(C(=C2C(C)C)O)O)C=O)C(=C1C3=C(C4=C(C=C3C)C(=C(C(=C4C=O)O)O)C(C)C)O)O
  • Recent ClinicalTrials:Safety, Tolerability, and Efficacy of AT101 in Patients With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
  • Description AT-101 (90141-22-3) is a small molecule mimic of the BH3 domain of cellular Bcl-2 inhibitors which interferes with the function of Bcl-2-family antiapoptotic proteins. AT-101 induces apoptosis in drug-resistant multiple myeloma cell lines. Apoptosis is activated by the mitochondrial pathway. Cell permeable.
  • Uses AT-101 is a BH3 mimetic known to be a potent inhibitor of antiapoptotic Bcl-2 family members.
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Total 8 Pictures about this product