(E)-2-(3-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-oxo-propyl)-benzoic acid

Base Information

Chemical Name:(E)-2-(3-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-oxo-propyl)-benzoic acid
CAS No.:1024634-12-5
Molecular Formula:C₂₇H₂₀ClNO₃
Molecular Weight:441.914
Hs Code.:

Synonyms:(E)-2-(3-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-oxo-propyl)-benzoic acid

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Chemical Property of (E)-2-(3-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-oxo-propyl)-benzoic acid

Chemical Property:

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Technology Process of (E)-2-(3-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-oxo-propyl)-benzoic acid

There total 2 articles about (E)-2-(3-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-oxo-propyl)-benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 878007-05-7
(E)-2-(3-(3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl)-2-methoxycarbonyl-3-oxo-propyl)-benzoic acid methyl ester

: 1024634-12-5
(E)-2-(3-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-oxo-propyl)-benzoic acid

: 149968-11-6
methyl 2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate

Guidance literature:: With hydrogenchloride; water; In acetic acid; at 25 - 65 ℃; for 10 - 12h;

Reference yield:

: 878007-05-7
(E)-2-(3-(3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl)-2-methoxycarbonyl-3-oxo-propyl)-benzoic acid methyl ester

: 1024634-12-5
(E)-2-(3-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-oxo-propyl)-benzoic acid

Guidance literature:: (E)-2-(3-(3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl)-2-methoxycarbonyl-3-oxo-propyl)-benzoic acid methyl ester; With hydrogenchloride; water; acetic acid; at 70 ℃; for 12h;

With water; ammonium chloride; at 30 ℃; for 2h;

Reference yield:

: 1024634-12-5
(E)-2-(3-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-oxo-propyl)-benzoic acid

: 74-88-4
methyl iodide

: 149968-11-6
methyl 2-(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-oxopropyl)benzoate

Guidance literature:: (E)-2-(3-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-oxo-propyl)-benzoic acid; With potassium carbonate; In acetone; at 30 ℃; for 0.5h;

methyl iodide; In acetone; at 55 ℃; for 12h; Product distribution / selectivity;