1-{2-[3-(Tert-butylamino)-2-hydroxypropoxy]phenyl}-3-phenyl-1-propanone hydrochloride

Base Information

Chemical Name:1-{2-[3-(Tert-butylamino)-2-hydroxypropoxy]phenyl}-3-phenyl-1-propanone hydrochloride
CAS No.:34183-26-1
Molecular Formula:C₂₂H₂₉NO₃*ClH
Molecular Weight:391.938
Hs Code.:
ChEMBL ID:CHEMBL1527349

Synonyms:MLS000533128;SMR000140566;1-{2-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-3-phenyl-1-propanone hydrochloride;Opera_ID_1303;MLS001384945;CHEMBL1527349;SR-01000215581;SR-01000215581-1

Suppliers and Price of 1-{2-[3-(Tert-butylamino)-2-hydroxypropoxy]phenyl}-3-phenyl-1-propanone hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-{2-[3-(Tert-butylamino)-2-hydroxypropoxy]phenyl}-3-phenyl-1-propanone hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:391.1914215
Heavy Atom Count:27
Complexity:412

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)NCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl

Technology Process of 1-{2-[3-(Tert-butylamino)-2-hydroxypropoxy]phenyl}-3-phenyl-1-propanone hydrochloride

There total 2 articles about 1-{2-[3-(Tert-butylamino)-2-hydroxypropoxy]phenyl}-3-phenyl-1-propanone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 75-64-9
tert-butylamine

: 22525-95-7
1-(2-(oxiran-2-ylmethoxy)phenyl)-3-phenylpropan-1-one

: 34183-26-1
C₂₂H₂₉NO₃*ClH

Guidance literature:: tert-butylamine; 1-(2-(oxiran-2-ylmethoxy)phenyl)-3-phenylpropan-1-one; In ethanol; at 160 ℃; for 0.25h; Microwave irradiation;

With hydrogenchloride; In methanol;
DOI:10.1021/jm2005546

Reference yield:

: 3516-95-8
2'-hydroxy-3-phenylpropiophenone

: 34183-26-1
C₂₂H₂₉NO₃*ClH

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / 18 h / Reflux

2: ethanol / 0.25 h / 160 °C / Microwave irradiation

With sodium hydroxide; In ethanol;
DOI:10.1021/jm2005546