((3R,4S)-4-(benzyloxy)-3-(4-methoxybenzyloxy)oct-7-enyloxy)(tert-butyl)diphenylsilane

Base Information

Chemical Name:((3R,4S)-4-(benzyloxy)-3-(4-methoxybenzyloxy)oct-7-enyloxy)(tert-butyl)diphenylsilane
CAS No.:1372785-71-1
Molecular Formula:C₃₉H₄₈O₄Si
Molecular Weight:608.893
Hs Code.:

Synonyms:((3R,4S)-4-(benzyloxy)-3-(4-methoxybenzyloxy)oct-7-enyloxy)(tert-butyl)diphenylsilane

Suppliers and Price of ((3R,4S)-4-(benzyloxy)-3-(4-methoxybenzyloxy)oct-7-enyloxy)(tert-butyl)diphenylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ((3R,4S)-4-(benzyloxy)-3-(4-methoxybenzyloxy)oct-7-enyloxy)(tert-butyl)diphenylsilane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ((3R,4S)-4-(benzyloxy)-3-(4-methoxybenzyloxy)oct-7-enyloxy)(tert-butyl)diphenylsilane

There total 12 articles about ((3R,4S)-4-(benzyloxy)-3-(4-methoxybenzyloxy)oct-7-enyloxy)(tert-butyl)diphenylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1372785-70-0
(3R,4S)-4-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)oct-7-en-3-ol

: 2746-25-0
p-Methoxybenzyl bromide

: 1372785-71-1
((3R,4S)-4-(benzyloxy)-3-(4-methoxybenzyloxy)oct-7-enyloxy)(tert-butyl)diphenylsilane

Guidance literature:: (3R,4S)-4-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)oct-7-en-3-ol; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

p-Methoxybenzyl bromide; In tetrahydrofuran; at 0 - 20 ℃; for 5h;
DOI:10.1016/j.tetasy.2012.02.009

Reference yield:

: 142561-88-4
(S)-1-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)but-3-en-1-ol

: 1372785-71-1
((3R,4S)-4-(benzyloxy)-3-(4-methoxybenzyloxy)oct-7-enyloxy)(tert-butyl)diphenylsilane

Guidance literature:: Multi-step reaction with 13 steps

1.1: sodium hydride / tetrahydrofuran; paraffin oil / 0 °C

1.2: 6 h / 20 °C

2.1: ozone / dichloromethane / 0.25 h / -78 °C

2.2: -78 °C

3.1: sodium tetrahydroborate / methanol / 0 - 20 °C

4.1: 1H-imidazole / dichloromethane / 0 - 20 °C

5.1: copper(II) choride dihydrate / acetonitrile / 0 - 20 °C

6.1: di(n-butyl)tin oxide; triethylamine / dichloromethane / 0.5 h / 20 °C

7.1: potassium carbonate / methanol / 1 h / 20 °C

8.1: magnesium / diethyl ether

8.2: 2 h / -40 - 20 °C

9.1: sodium hydride / tetrahydrofuran; paraffin oil / 0.5 h / 0 °C

9.2: 5 h / 20 °C

10.1: water; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 1 h / 20 °C

11.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere

12.1: methanol; potassium carbonate / 2 h / 20 °C

13.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C

13.2: 5 h / 0 - 20 °C

With 1H-imidazole; methanol; sodium tetrahydroborate; copper(II) choride dihydrate; di-isopropyl azodicarboxylate; water; sodium hydride; di(n-butyl)tin oxide; potassium carbonate; ozone; magnesium; triethylamine; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; acetonitrile; paraffin oil; 11.1: Mitsunobu reaction;
DOI:10.1016/j.tetasy.2012.02.009

Reference yield:

: 1372785-68-6
(3S,4S)-4-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)oct-7-en-3-ol

: 1372785-71-1
((3R,4S)-4-(benzyloxy)-3-(4-methoxybenzyloxy)oct-7-enyloxy)(tert-butyl)diphenylsilane

Guidance literature:: Multi-step reaction with 3 steps

1.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere

2.1: methanol; potassium carbonate / 2 h / 20 °C

3.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C

3.2: 5 h / 0 - 20 °C

With methanol; di-isopropyl azodicarboxylate; sodium hydride; potassium carbonate; triphenylphosphine; In tetrahydrofuran; 1.1: Mitsunobu reaction;
DOI:10.1016/j.tetasy.2012.02.009