2,5-dimethyl-3-(4-fluorophenyl)-1-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Base Information

Chemical Name:2,5-dimethyl-3-(4-fluorophenyl)-1-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
CAS No.:141307-02-0
Molecular Formula:C₂₂H₂₃FN₂
Molecular Weight:334.436
Hs Code.:

Synonyms:2,5-dimethyl-3-(4-fluorophenyl)-1-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Suppliers and Price of 2,5-dimethyl-3-(4-fluorophenyl)-1-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 2,5-dimethyl-3-(4-fluorophenyl)-1-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Chemical Property:

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 2,5-dimethyl-3-(4-fluorophenyl)-1-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

There total 4 articles about 2,5-dimethyl-3-(4-fluorophenyl)-1-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-[3-(4-Fluoro-phenyl)-2,5-dimethyl-indol-1-yl]-1-methyl-pyridinium; iodide

: 141307-02-0
2,5-dimethyl-3-(4-fluorophenyl)-1-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Guidance literature:: With sodium tetrahydroborate; In ethanol; for 3.5h;
DOI:10.1021/jm00104a007

Reference yield:

: 19524-06-2
4-bromopyridine hydrochloride

: 141307-02-0
2,5-dimethyl-3-(4-fluorophenyl)-1-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Guidance literature:: Multi-step reaction with 3 steps

1: 31 percent / K₂CO₃, CuBr / various solvent(s) / 18 h / Heating

2: acetone / 40 °C

3: NaBH₄ / ethanol / 3.5 h

With sodium tetrahydroborate; potassium carbonate; copper(I) bromide; In ethanol; acetone;
DOI:10.1021/jm00104a007

Reference yield:

: 141306-71-0
2,5-dimethyl-3-(4-fluorophenyl)-1H-indole

: 141307-02-0
2,5-dimethyl-3-(4-fluorophenyl)-1-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

Guidance literature:: Multi-step reaction with 3 steps

1: 31 percent / K₂CO₃, CuBr / various solvent(s) / 18 h / Heating

2: acetone / 40 °C

3: NaBH₄ / ethanol / 3.5 h

With sodium tetrahydroborate; potassium carbonate; copper(I) bromide; In ethanol; acetone;
DOI:10.1021/jm00104a007