17-[6-fluoro-4'(1H)-oxo-3'-phenyl-2'-thioxoquinazolin-1-yl]androst-4-en-3-one

Base Information

Chemical Name:17-[6-fluoro-4'(1H)-oxo-3'-phenyl-2'-thioxoquinazolin-1-yl]androst-4-en-3-one
CAS No.:1346667-62-6
Molecular Formula:C₃₃H₃₅FN₂O₂S
Molecular Weight:542.718
Hs Code.:

Synonyms:17-[6-fluoro-4'(1H)-oxo-3'-phenyl-2'-thioxoquinazolin-1-yl]androst-4-en-3-one

Suppliers and Price of 17-[6-fluoro-4'(1H)-oxo-3'-phenyl-2'-thioxoquinazolin-1-yl]androst-4-en-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 17-[6-fluoro-4'(1H)-oxo-3'-phenyl-2'-thioxoquinazolin-1-yl]androst-4-en-3-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 17-[6-fluoro-4'(1H)-oxo-3'-phenyl-2'-thioxoquinazolin-1-yl]androst-4-en-3-one

There total 3 articles about 17-[6-fluoro-4'(1H)-oxo-3'-phenyl-2'-thioxoquinazolin-1-yl]androst-4-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1346667-59-1
2-(3-oxoandrost-4-en-17yl-amino)-5-fluorobenzoic acid

: 103-72-0
phenyl isothiocyanate

: 1346667-62-6
17-[6-fluoro-4'(1H)-oxo-3'-phenyl-2'-thioxoquinazolin-1-yl]androst-4-en-3-one

Guidance literature:: With triethylamine; In ethanol; Reflux;
DOI:10.1016/j.bmc.2011.09.033

Reference yield:

: 58-22-0
testosterone

: 1346667-62-6
17-[6-fluoro-4'(1H)-oxo-3'-phenyl-2'-thioxoquinazolin-1-yl]androst-4-en-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / diethyl ether / 20 °C / Cooling with ice

2: ethanol / Reflux

3: triethylamine / ethanol / Reflux

With thionyl chloride; triethylamine; In diethyl ether; ethanol;
DOI:10.1016/j.bmc.2011.09.033

Reference yield:

: 911651-92-8
17-chloroandrost-4-en-3-one

: 1346667-62-6
17-[6-fluoro-4'(1H)-oxo-3'-phenyl-2'-thioxoquinazolin-1-yl]androst-4-en-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / Reflux

2: triethylamine / ethanol / Reflux

With triethylamine; In ethanol;
DOI:10.1016/j.bmc.2011.09.033