methyl 2-benzyl-3-(2-(4-cyanobenzyl)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-ylamino)-3-oxopropanoate

Base Information

Chemical Name:methyl 2-benzyl-3-(2-(4-cyanobenzyl)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-ylamino)-3-oxopropanoate
CAS No.:1026018-15-4
Molecular Formula:C₂₈H₂₅N₃O₅
Molecular Weight:483.524
Hs Code.:

Synonyms:methyl 2-benzyl-3-(2-(4-cyanobenzyl)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-ylamino)-3-oxopropanoate

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Chemical Property of methyl 2-benzyl-3-(2-(4-cyanobenzyl)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-ylamino)-3-oxopropanoate

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Technology Process of methyl 2-benzyl-3-(2-(4-cyanobenzyl)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-ylamino)-3-oxopropanoate

There total 1 articles about methyl 2-benzyl-3-(2-(4-cyanobenzyl)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-ylamino)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.9%

: 1026018-01-8
4-((7-amino-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl)methyl)benzonitrile

: 54561-75-0
2-benzyl-3-methoxy-3-oxopropanoic acid

: 1026018-15-4
methyl 2-benzyl-3-(2-(4-cyanobenzyl)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-ylamino)-3-oxopropanoate

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide; at 20 ℃; pH=7;
DOI:10.1021/jm701622y

Reference yield:

: 1026018-15-4
methyl 2-benzyl-3-(2-(4-cyanobenzyl)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-ylamino)-3-oxopropanoate

: 1026018-16-5
C₂₈H₂₈N₄O₅

Guidance literature:: methyl 2-benzyl-3-(2-(4-cyanobenzyl)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-ylamino)-3-oxopropanoate; With hydrogenchloride; In methanol; at 20 ℃; for 24h;

With ammonium acetate; In ethanol; for 48h; Further stages.;
DOI:10.1021/jm701622y