[4-(4-methoxycarbonylbutyl)phenyl]-(2,4,6-trimethylphenyl)phosphinic acid ethyl ester

Base Information

Chemical Name:[4-(4-methoxycarbonylbutyl)phenyl]-(2,4,6-trimethylphenyl)phosphinic acid ethyl ester
CAS No.:408316-37-0
Molecular Formula:C₂₃H₃₁O₄P
Molecular Weight:402.471
Hs Code.:

Synonyms:[4-(4-methoxycarbonylbutyl)phenyl]-(2,4,6-trimethylphenyl)phosphinic acid ethyl ester

Suppliers and Price of [4-(4-methoxycarbonylbutyl)phenyl]-(2,4,6-trimethylphenyl)phosphinic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [4-(4-methoxycarbonylbutyl)phenyl]-(2,4,6-trimethylphenyl)phosphinic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [4-(4-methoxycarbonylbutyl)phenyl]-(2,4,6-trimethylphenyl)phosphinic acid ethyl ester

There total 4 articles about [4-(4-methoxycarbonylbutyl)phenyl]-(2,4,6-trimethylphenyl)phosphinic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 408316-41-6
2,4,6-trimethylphenylphosphinic acid ethyl ester

: 408316-46-1
methyl 5-(4-iodophenyl)pentanoate

: 408316-37-0
[4-(4-methoxycarbonylbutyl)phenyl]-(2,4,6-trimethylphenyl)phosphinic acid ethyl ester

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; triethylamine; In acetonitrile; at 65 ℃; for 19h;
DOI:10.1016/S0040-4020(01)01048-1

Reference yield:

: 20620-59-1
5-phenyl-n-valeric acid methyl ester

: 408316-37-0
[4-(4-methoxycarbonylbutyl)phenyl]-(2,4,6-trimethylphenyl)phosphinic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: Tl(OOCCF₃)3 / trifluoroacetic acid / 120 h / 20 °C

1.2: 93 percent / KI / trifluoroacetic acid; H₂O / 0.25 h

2.1: 48 percent / Pd(OAc)2; dppf; Et₃N / acetonitrile / 19 h / 65 °C

With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; triethylamine; thallium(III) trifluoroacetate; In acetonitrile; trifluoroacetic acid;
DOI:10.1016/S0040-4020(01)01048-1

Reference yield:

: 408316-47-2
diethyl (2,4,6-trimethylphenyl)phosphonite

: 408316-37-0
[4-(4-methoxycarbonylbutyl)phenyl]-(2,4,6-trimethylphenyl)phosphinic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / 0.1 M HCl / tetrahydrofuran / 2.5 h / 50 °C

2: 48 percent / Pd(OAc)2; dppf; Et₃N / acetonitrile / 19 h / 65 °C

With hydrogenchloride; 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; triethylamine; In tetrahydrofuran; acetonitrile;
DOI:10.1016/S0040-4020(01)01048-1