Technology Process of ethyl (benzyl 6,7-dideoxy-2,3-O-isopropylidene-α-D-talo-octopyranosid)uronate
There total 10 articles about ethyl (benzyl 6,7-dideoxy-2,3-O-isopropylidene-α-D-talo-octopyranosid)uronate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate;
In
ethanol;
for 0.5h;
Ambient temperature;
DOI:10.1246/bcsj.65.567
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 75 percent / pyridine / CH2Cl2 / 2 h / Ambient temperature
2: 94.3 percent / 2-naphthalenesulfonic acid / acetone / 8 h / Ambient temperature
3: 94 percent / triethylamine / tetrahydrofuran / Ambient temperature
4: 1.) Na / 1.) toluene, reflux, 2.) toluene, reflux, overnight
5: 70 percent / DMSO, NaCl / H2O / 15 h / 145 °C
6: 1 g / 1 M aq. KOH / methanol / Ambient temperature
7: 96 percent / diethyl ether
8: 95 percent / pyridinium chlorochromate (PCC) / CH2Cl2 / Ambient temperature
9: 97 percent / NaBH4 / ethanol / 0.5 h / Ambient temperature
With
pyridine; potassium hydroxide; sodium tetrahydroborate; naphthalene-2-sulfonate; sodium; dimethyl sulfoxide; triethylamine; pyridinium chlorochromate; sodium chloride;
In
tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; water; acetone;
DOI:10.1246/bcsj.65.567
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 94.3 percent / 2-naphthalenesulfonic acid / acetone / 8 h / Ambient temperature
2: 94 percent / triethylamine / tetrahydrofuran / Ambient temperature
3: 1.) Na / 1.) toluene, reflux, 2.) toluene, reflux, overnight
4: 70 percent / DMSO, NaCl / H2O / 15 h / 145 °C
5: 1 g / 1 M aq. KOH / methanol / Ambient temperature
6: 96 percent / diethyl ether
7: 95 percent / pyridinium chlorochromate (PCC) / CH2Cl2 / Ambient temperature
8: 97 percent / NaBH4 / ethanol / 0.5 h / Ambient temperature
With
potassium hydroxide; sodium tetrahydroborate; naphthalene-2-sulfonate; sodium; dimethyl sulfoxide; triethylamine; pyridinium chlorochromate; sodium chloride;
In
tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; water; acetone;
DOI:10.1246/bcsj.65.567
