C₂₅H₂₉O₅P

Base Information

• Chemical Name: C₂₅H₂₉O₅P
• CAS No.: 95821-72-0
• Molecular Formula: C₂₅H₂₉O₅P
• Molecular Weight: 440.476
• Mol file: 95821-72-0.mol

Synonyms:C₂₅H₂₉O₅P

Chemical Property of C₂₅H₂₉O₅P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₂₅H₂₉O₅P

There total 2 articles about C₂₅H₂₉O₅P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4,4'-dimethoxytrityl chloride (40615-36-9) + triethyl phosphite (122-52-1) → C25H29O5P (95821-72-0)

Guidance literature:

In benzene; for 2h; Reflux;

DOI:10.1021/ja8020999

Reference yield: 80.0%

4,4'-dimethoxytrityl alcohol (40615-35-8) + phosphonic acid diethyl ester (762-04-9) → C25H29O5P (95821-72-0)

Guidance literature:

With trifluorormethanesulfonic acid; In nitromethane; at 75 ℃; for 24h;

DOI:10.1039/c7ob02970e

upstream raw materials:

4,4'-dimethoxytrityl chloride

triethyl phosphite

4,4'-dimethoxytrityl alcohol

phosphonic acid diethyl ester

Refernces

• 1、 Palchaudhuri, Rahul,Nesterenko, Vitaliy,Hergenrother, Paul J.. "The complex role of the triphenylmethyl motif in anticancer compounds". supporting information; experimental part. p. 10274 - 10281. Retrieved 2009/02/04.