(4-(trifluoromethyl)phenyl)zinc(II) bromide

Base Information

• Chemical Name: (4-(trifluoromethyl)phenyl)zinc(II) bromide
• CAS No.: 198345-82-3
• Molecular Formula: C₇H₄BrF₃Zn
• Molecular Weight: 290.398
• Mol file: 198345-82-3.mol

Synonyms:(4-(trifluoromethyl)phenyl)zinc(II) bromide

Chemical Property of (4-(trifluoromethyl)phenyl)zinc(II) bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-(trifluoromethyl)phenyl)zinc(II) bromide

There total 5 articles about (4-(trifluoromethyl)phenyl)zinc(II) bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

p-trifluoromethylphenyl bromide (402-43-7) + zinc (7440-66-6) → (4-(trifluoromethyl)phenyl)zinc(II) bromide (198345-82-3) + 4,4'-bis(trifluoromethyl)biphenyl (581-80-6) + α,α,α-trifluorotoluene (98-08-8)

Guidance literature:

With trifluoroacetic acid; cobalt(II) bromide; zinc dibromide; In acetonitrile; the mixt. in CH3CN was stirred at room temp., then arylbromide was added, stirred at room temp.; GC analysis;

DOI:10.1021/ja0289494

Reference yield:

p-trifluoromethylphenyl bromide (402-43-7) + zinc (7440-66-6) → (4-(trifluoromethyl)phenyl)zinc(II) bromide (198345-82-3)

Guidance literature:

zinc; With cobalt 2,2'-bipyridine dibromide; 3-chloroprop-1-ene; trifluoroacetic acid; In acetonitrile;

p-trifluoromethylphenyl bromide; In acetonitrile;

DOI:10.1039/c2cc36676b

Reference yield:

p-trifluoromethylphenyl bromide (402-43-7) → (4-(trifluoromethyl)phenyl)zinc(II) bromide (198345-82-3)

Guidance literature:

With zinc; at 20 ℃; for 1h;

DOI:10.1002/bkcs.10217

upstream raw materials:

p-trifluoromethylphenyl bromide

zinc

zinc dibromide

(4-trifluoromethylphenyl)lithium

Downstream raw materials:

(E)-6-o-tolyl-5-(4-trifluoromethyl-phenyl)-hex-5-enenitrile

3-bromo-2-methyl-5-(4-(trifluoromethyl)phenyl)thiophene

phenyl[4-(trifluoromethyl)phenyl]methanone

C₁₉H₁₅F₃O₃

Refernces

• 1、 Bourne-Branchu, Yann,Moncomble, Aurélien,Corpet, Martin,Danoun, Gregory,Gosmini, Corinne. "Cobalt-Catalyzed Oxidative Homocoupling of Arylzinc Species". . p. 3352 - 3356. Retrieved 2016/09/12.
• 2、 Huang, Chung-Yang,Doyle, Abigail G.. "Electron-deficient olefin ligands enable generation of quaternary carbons by Ni-catalyzed cross-coupling". supporting information. p. 5638 - 5641. Retrieved 2015/05/20.