2,5‐dimethoxyterephthalohydrazide

Base Information

• Chemical Name: 2,5‐dimethoxyterephthalohydrazide
• CAS No.: 114503-42-3
• Molecular Formula: C₁₀H₁₄N₄O₄
• Molecular Weight: 254.246
• Mol file: 114503-42-3.mol

Synonyms:2,5‐dimethoxyterephthalohydrazide

Chemical Property of 2,5‐dimethoxyterephthalohydrazide

Chemical Property:

• Density: 1.320±0.06 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

2,5-Dimethoxyterephthalohydrazide 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5‐dimethoxyterephthalohydrazide

There total 6 articles about 2,5‐dimethoxyterephthalohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

diethyl-2,5-dimethoxy-1,4-benzenedicarboxylate (173267-23-7) → 2,5‐dimethoxyterephthalohydrazide (114503-42-3)

Guidance literature:

With hydrazine hydrate; In ethanol; for 15h; Schlenk technique; Reflux;

DOI:10.1002/chem.202100398

Reference yield: 94.0%

dimethyl 2,5-diethoxyterephthalate → 2,5‐dimethoxyterephthalohydrazide (114503-42-3)

Guidance literature:

With hydrazine hydrate; In ethanol; for 15h; Reflux;

DOI:10.1039/d1dt00186h

Reference yield: 90.7%

2,5-dimethoxyterephthalic acid dimethyl ester (21004-12-6) → 2,5‐dimethoxyterephthalohydrazide (114503-42-3)

Guidance literature:

With hydrazine hydrate; In methanol; toluene; for 24h; Reflux; Inert atmosphere;

DOI:10.1021/jacs.0c08436

upstream raw materials:

1,4-dibromo-2,5-dimethoxybenzene

diethyl-2,5-dimethoxy-1,4-benzenedicarboxylate

1,4-dimethoxybezene

2,5-dimethoxyterephthalic acid dimethyl ester