methyl (2R)-4-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2-methylsulfonyloxy-butanoate

Base Information

Chemical Name:methyl (2R)-4-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2-methylsulfonyloxy-butanoate
CAS No.:906545-82-2
Molecular Formula:C₄₀H₄₆O₁₀S
Molecular Weight:718.865
Hs Code.:

Synonyms:methyl (2R)-4-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2-methylsulfonyloxy-butanoate

Suppliers and Price of methyl (2R)-4-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2-methylsulfonyloxy-butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (2R)-4-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2-methylsulfonyloxy-butanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (2R)-4-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2-methylsulfonyloxy-butanoate

There total 5 articles about methyl (2R)-4-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2-methylsulfonyloxy-butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 906545-79-7
methyl (2S)-2-hydroxy-4-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-butanoate

: 75-75-2,98527-29-8
methanesulfonic acid

: 906545-82-2
methyl (2R)-4-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2-methylsulfonyloxy-butanoate

Guidance literature:: With dmap; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 70 ℃; for 2h;
DOI:10.1021/ol061100y

Reference yield:

: 906545-77-5
(2,3,4,6-tetra-O-benzyl-1-C-vinyl-α-D-galactopyranosyloxy)-ethanoic acid

: 906545-82-2
methyl (2R)-4-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2-methylsulfonyloxy-butanoate

Guidance literature:: Multi-step reaction with 4 steps

1: lithium diisopropylamide / tetrahydrofuran; heptane; ethylbenzene / 1 h / -78 °C

2: 1.60 g / diethyl ether / 0 °C

3: 91 percent / hydrogen / Pt/C / methanol / 5 h / 20 °C

4: 90 percent / triphenylphosphine; DMAP; diethyl azodicarboxylate / tetrahydrofuran / 2 h / 70 °C

With dmap; hydrogen; triphenylphosphine; lithium diisopropyl amide; diethylazodicarboxylate; platinum on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; n-heptane; ethylbenzene; 1: <2,3>-Wittig sigmatropic rearrangement / 4: Mitsunobu reaction;
DOI:10.1021/ol061100y

Reference yield:

: 906545-78-6
(S)-2-Hydroxy-4-[(3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-(2Z)-ylidene]-butyric acid methyl ester

: 906545-82-2
methyl (2R)-4-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-2-methylsulfonyloxy-butanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / hydrogen / Pt/C / methanol / 5 h / 20 °C

2: 90 percent / triphenylphosphine; DMAP; diethyl azodicarboxylate / tetrahydrofuran / 2 h / 70 °C

With dmap; hydrogen; triphenylphosphine; diethylazodicarboxylate; platinum on activated charcoal; In tetrahydrofuran; methanol; 2: Mitsunobu reaction;
DOI:10.1021/ol061100y