Leucine, N-stearoyl-, L-

Base Information

• Chemical Name: Leucine, N-stearoyl-, L-
• CAS No.: 14379-43-2
• Molecular Formula: C₂₄H₄₇NO₃
• Molecular Weight: 397.642
• Hs Code.: 2924199090
• DSSTox Substance ID: DTXSID10162547
• Nikkaji Number: J523.463H
• Wikidata: Q76085100
• Mol file: 14379-43-2.mol

Synonyms:Leucine, N-stearoyl-, L-;N-Octadecanoylleucine;N-Stearoyl-L-leucine;14379-43-2;L-Leucine, N-(1-oxooctadecyl)-;L-Leucine, N-stearoyl-;(2S)-4-methyl-2-(octadecanoylamino)pentanoic acid;N-Stearoylleucine;STEAROYL LEUCINE;SCHEMBL2910119;C24H47NO3;DTXSID10162547;L-Leucine, N-stearoyl- (6CI);C24-H47-N-O3;LS-87868

Chemical Property of Leucine, N-stearoyl-, L-

Chemical Property:

• Vapor Pressure: 1.41E-13mmHg at 25°C
• Boiling Point: 550.6°Cat760mmHg
• Flash Point: 286.8°C
• PSA: 69.89000
• Density: 0.933g/cm³
• LogP: 7.70370
• XLogP3: 9.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 20
• Exact Mass: 397.35559436
• Heavy Atom Count: 28
• Complexity: 382

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)NC(CC(C)C)C(=O)O
• Isomeric SMILES: CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)O

Technology Process of Leucine, N-stearoyl-, L-

There total 7 articles about Leucine, N-stearoyl-, L- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

stearic acid N-hydroxysuccinimide ester (14464-32-5) + L-leucine (61-90-5,21675-61-6,25248-98-0,70-45-1) → N-octadecanoyl leucine (14379-43-2)

Guidance literature:

With sodium hydrogencarbonate; In water; at 0 - 20 ℃;

DOI:10.1246/bcsj.20120220

Reference yield: 81.0%

L-leucine (61-90-5,21675-61-6,25248-98-0,70-45-1) + stearic acid (57-11-4) → N-octadecanoyl leucine (14379-43-2)

Guidance literature:

With sodium hydrogencarbonate; In water; at 0 - 20 ℃;

DOI:10.1246/bcsj.20120220

Reference yield:

(L)-leucine sodium salt (34237-21-3,67607-44-7,118604-74-3) + Stearoyl chloride (112-76-5) → N-octadecanoyl leucine (14379-43-2)

Guidance literature:

In water; at 40 - 50 ℃; for 1h; pH 9.5-10.5;

upstream raw materials:

N-stearoyl-L-leucine methyl ester

(L)-leucine sodium salt

Stearoyl chloride

(S)-Leu-OMe