4aα-ethyl-7α-<1-(4-methoxy-2-aminophenyl)ethenyl>-2,4a,5,6,7,7aα-hexahydro-1H-1-pyrindin-7-ol

Base Information

Chemical Name:4aα-ethyl-7α-<1-(4-methoxy-2-aminophenyl)ethenyl>-2,4a,5,6,7,7aα-hexahydro-1H-1-pyrindin-7-ol
CAS No.:86045-73-0
Molecular Formula:C₁₉H₂₆N₂O₂
Molecular Weight:314.428
Hs Code.:

Synonyms:4aα-ethyl-7α-<1-(4-methoxy-2-aminophenyl)ethenyl>-2,4a,5,6,7,7aα-hexahydro-1H-1-pyrindin-7-ol

Suppliers and Price of 4aα-ethyl-7α-<1-(4-methoxy-2-aminophenyl)ethenyl>-2,4a,5,6,7,7aα-hexahydro-1H-1-pyrindin-7-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4aα-ethyl-7α-<1-(4-methoxy-2-aminophenyl)ethenyl>-2,4a,5,6,7,7aα-hexahydro-1H-1-pyrindin-7-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4aα-ethyl-7α-<1-(4-methoxy-2-aminophenyl)ethenyl>-2,4a,5,6,7,7aα-hexahydro-1H-1-pyrindin-7-ol

There total 11 articles about 4aα-ethyl-7α-<1-(4-methoxy-2-aminophenyl)ethenyl>-2,4a,5,6,7,7aα-hexahydro-1H-1-pyrindin-7-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 86045-71-8
6aα-ethyl-8aα-<1-<4-methoxy-2-(trimethylacetamido)-phenyl>ethenyl>-1,2,4,6a,7,8,8a,8bα-octahydro-1-oxacyclopentindolizin-2-one

: 86045-73-0
4aα-ethyl-7α-<1-(4-methoxy-2-aminophenyl)ethenyl>-2,4a,5,6,7,7aα-hexahydro-1H-1-pyrindin-7-ol

Guidance literature:: With potassium hydroxide; In methanol; water; for 8h; Heating;
DOI:10.1021/jo00164a011

Reference yield:

: 59557-92-5
2-bromo-5-methoxyaniline

: 86045-73-0
4aα-ethyl-7α-<1-(4-methoxy-2-aminophenyl)ethenyl>-2,4a,5,6,7,7aα-hexahydro-1H-1-pyrindin-7-ol

Guidance literature:: Multi-step reaction with 5 steps

2: 88 percent / KCN-18-crown-6-complex / CHCl₃ / 0.5 h / Ambient temperature

4: 1.) n-BuLi / 1.) THF, hexane, -78 deg C to room temp., 15 min, 2.) -78 deg C to room temp., 36 h

5: 96 percent / KOH / methanol; H₂O / 8 h / Heating

With potassium hydroxide; n-butyllithium; (K-18-crown-6 ether) cyanide; In methanol; chloroform; water;
DOI:10.1021/jo00164a011

Reference yield:

: 86045-69-4
4-methoxy-2-(trimethylacetamido)benzaldehyde

: 86045-73-0
4aα-ethyl-7α-<1-(4-methoxy-2-aminophenyl)ethenyl>-2,4a,5,6,7,7aα-hexahydro-1H-1-pyrindin-7-ol

Guidance literature:: Multi-step reaction with 4 steps

1: 88 percent / KCN-18-crown-6-complex / CHCl₃ / 0.5 h / Ambient temperature

3: 1.) n-BuLi / 1.) THF, hexane, -78 deg C to room temp., 15 min, 2.) -78 deg C to room temp., 36 h

4: 96 percent / KOH / methanol; H₂O / 8 h / Heating

With potassium hydroxide; n-butyllithium; (K-18-crown-6 ether) cyanide; In methanol; chloroform; water;
DOI:10.1021/jo00164a011