86045-69-4Relevant articles and documents
A New Approach for the Total Synthesis of Pentacyclic Aspidosperma Alkaloids. Total Synthesis of dl-16-Methoxytabersonine
Overman, Larry E.,Sworin, Michael,Burk, Robert M.
, p. 2685 - 2690 (1983)
The pentacyclic Aspidosperma alkaloid dl-16-methoxytabersonine (1) has been synthesized by an efficient convergent sequence.The key step in the synthesis is the "ring-enlarging pyrrolidine annulation" reaction of 7-styrylhydropyridin-7-ols 17 and 18 to gi