4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoic acid

Base Information

• Chemical Name: 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoic acid
• CAS No.: 1416698-95-7
• Molecular Formula: C₁₇H₁₇NO₅S
• Molecular Weight: 347.392
• Mol file: 1416698-95-7.mol

Synonyms:4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoic acid

Chemical Property of 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoic acid

There total 4 articles about 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

methyl 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoate (1416698-93-5) → 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoic acid (1416698-95-7)

Guidance literature:

With water; sodium hydroxide; In tetrahydrofuran; at 25 - 30 ℃; for 3h;

DOI:10.1016/j.ejmech.2012.10.005

Reference yield:

methyl 4-((methylsulfinyl)methyl)benzoate (199534-98-0) → 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoic acid (1416698-95-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium azide; sulfuric acid / chloroform / 15 h / -20 - 50 °C / Inert atmosphere

2: pyridine / dichloromethane; toluene / 3 h / 15 - 30 °C / Inert atmosphere

3: water; sodium hydroxide / tetrahydrofuran / 3 h / 25 - 30 °C

With pyridine; sodium azide; sulfuric acid; water; sodium hydroxide; In tetrahydrofuran; dichloromethane; chloroform; toluene;

DOI:10.1016/j.ejmech.2012.10.005

Reference yield:

methyl 4-[(methylsulfanyl)methyl]benzoate (67003-49-0) → 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoic acid (1416698-95-7)

Guidance literature:

Multi-step reaction with 4 steps

1: dihydrogen peroxide; vanadium(V) oxide / acetonitrile / 5 h / -20 - 30 °C / Inert atmosphere

2: sodium azide; sulfuric acid / chloroform / 15 h / -20 - 50 °C / Inert atmosphere

3: pyridine / dichloromethane; toluene / 3 h / 15 - 30 °C / Inert atmosphere

4: water; sodium hydroxide / tetrahydrofuran / 3 h / 25 - 30 °C

With pyridine; sodium azide; vanadium(V) oxide; sulfuric acid; water; dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; dichloromethane; chloroform; toluene; acetonitrile;

DOI:10.1016/j.ejmech.2012.10.005

upstream raw materials:

methyl 4-((methylsulfinyl)methyl)benzoate

methyl 4-[(methylsulfanyl)methyl]benzoate

methyl 4-((S-methylsulfonimidoyl)methyl)benzoate

methyl 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoate

Downstream raw materials:

C₂₁H₁₈Cl₂N₄O₃S