methyl 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoate

Base Information

• Chemical Name: methyl 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoate
• CAS No.: 1416698-93-5
• Molecular Formula: C₁₈H₁₉NO₅S
• Molecular Weight: 361.419
• Mol file: 1416698-93-5.mol

Synonyms:methyl 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoate

Chemical Property of methyl 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoate

There total 2 articles about methyl 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl 4-((S-methylsulfonimidoyl)methyl)benzoate (1416698-90-2) + benzyl chloroformate (501-53-1,94274-21-2) → methyl 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoate (1416698-93-5)

Guidance literature:

With pyridine; In dichloromethane; toluene; at 15 - 30 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.ejmech.2012.10.005

Reference yield:

methyl 4-((methylsulfinyl)methyl)benzoate (199534-98-0) → methyl 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoate (1416698-93-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide; sulfuric acid / chloroform / 15 h / -20 - 50 °C / Inert atmosphere

2: pyridine / dichloromethane; toluene / 3 h / 15 - 30 °C / Inert atmosphere

With pyridine; sodium azide; sulfuric acid; In dichloromethane; chloroform; toluene;

DOI:10.1016/j.ejmech.2012.10.005

Reference yield: 82.0%

methyl 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoate (1416698-93-5) → 4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoic acid (1416698-95-7)

Guidance literature:

With water; sodium hydroxide; In tetrahydrofuran; at 25 - 30 ℃; for 3h;

DOI:10.1016/j.ejmech.2012.10.005

upstream raw materials:

methyl 4-((methylsulfinyl)methyl)benzoate

methyl 4-((S-methylsulfonimidoyl)methyl)benzoate

benzyl chloroformate

Downstream raw materials:

4-((N-((benzyloxy)carbonyl)-S-methylsulfonimidoyl)methyl)benzoic acid

C₂₁H₁₈Cl₂N₄O₃S