(S)-mandelic acid salt of (1R,2R)-2-trans-2-(benzylamino)cyclohexanol

Base Information

Chemical Name:(S)-mandelic acid salt of (1R,2R)-2-trans-2-(benzylamino)cyclohexanol
CAS No.:882409-01-0
Molecular Formula:C₈H₈O₃*C₁₃H₁₉NO
Molecular Weight:357.45
Hs Code.:

Synonyms:(S)-mandelic acid salt of (1R,2R)-2-trans-2-(benzylamino)cyclohexanol

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Chemical Property of (S)-mandelic acid salt of (1R,2R)-2-trans-2-(benzylamino)cyclohexanol

Chemical Property:

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Technology Process of (S)-mandelic acid salt of (1R,2R)-2-trans-2-(benzylamino)cyclohexanol

There total 4 articles about (S)-mandelic acid salt of (1R,2R)-2-trans-2-(benzylamino)cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17199-29-0
(S)-Mandelic acid

: 40571-86-6,40571-87-7,51925-39-4,131164-07-3,141553-09-5
rac-(1R,2R)-2-(benzylamino)cyclohexanol

: 882409-01-0
(S)-mandelic acid salt of (1R,2R)-2-trans-2-(benzylamino)cyclohexanol

Guidance literature:: In ethyl acetate; at 0 - 20 ℃; enantioselective reaction; Resolution of racemate;
DOI:10.3184/174751914X13977299691549

Reference yield:

: 100-46-9
benzylamine

: 882409-01-0
(S)-mandelic acid salt of (1R,2R)-2-trans-2-(benzylamino)cyclohexanol

Guidance literature:: Multi-step reaction with 2 steps

1: water / 3.5 h / 95 °C

2: ethyl acetate / 0 - 20 °C / Resolution of racemate

In water; ethyl acetate;
DOI:10.3184/174751914X13977299691549

Reference yield:

: 286-20-4
cyclohexane-1,2-epoxide

: 882409-01-0
(S)-mandelic acid salt of (1R,2R)-2-trans-2-(benzylamino)cyclohexanol

Guidance literature:: Multi-step reaction with 2 steps

1: water / 3.5 h / 95 °C

2: ethyl acetate / 0 - 20 °C / Resolution of racemate

In water; ethyl acetate;
DOI:10.3184/174751914X13977299691549