4,10,16,22-tetra-p-toluenesulfonyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane

Base Information

• Chemical Name: 4,10,16,22-tetra-p-toluenesulfonyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane
• CAS No.: 177089-49-5
• Molecular Formula: C₄₄H₆₀N₄O₁₂S₄
• Molecular Weight: 965.244
• Mol file: 177089-49-5.mol

Synonyms:4,10,16,22-tetra-p-toluenesulfonyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane

Chemical Property of 4,10,16,22-tetra-p-toluenesulfonyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,10,16,22-tetra-p-toluenesulfonyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane

There total 6 articles about 4,10,16,22-tetra-p-toluenesulfonyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

N,N'-Bis(p-tolylsulfonyl)-1,5-diamino-3-oxapentane (59945-34-5) + 3-oxa-1,5-dichloropentane (111-44-4) → 4,10-bis(p-tolylsulphonyl)-1,7-dioxa-4,10-diazacyclododecane (52601-77-1) + 4,10,16,22-tetra-p-toluenesulfonyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane (177089-49-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 16h;

DOI:10.1039/b203285f

Reference yield: 43.0%

N,N'-Bis(p-tolylsulfonyl)-1,5-diamino-3-oxapentane (59945-34-5) + 3-oxa-1,5-dichloropentane (111-44-4) → 4,10-bis(p-tolylsulphonyl)-1,7-dioxa-4,10-diazacyclododecane (52601-77-1) + 4,10,16,22-tetra-p-toluenesulfonyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane (177089-49-5) + 4,10,16,22,28,34-hexakis-(toluene-4-sulfonyl)-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaaza-cyclohexatriacontane

Guidance literature:

In N,N-dimethyl-formamide; Title compound not separated from byproducts;

DOI:10.1039/b203285f

Reference yield:

N,N-bis<2-<2-<(p-tolylsulfonyl)oxy>ethoxy>ethyl>-p-toluenesulfonamide (118187-55-6) + 1,6,11-tris-(p-tolylsulphonyl)-3,9-dioxa-6-azaundecane-1,11-diamine (132930-18-8) → 4,10,16,22-tetra-p-toluenesulfonyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane (177089-49-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 96h;

DOI:10.1021/jo952283x

upstream raw materials:

N,N-bis<2-<2-<(p-tolylsulfonyl)oxy>ethoxy>ethyl>-p-toluenesulfonamide

1,6,11-tris-(p-tolylsulphonyl)-3,9-dioxa-6-azaundecane-1,11-diamine

N,N'-Bis(p-tolylsulfonyl)-1,5-diamino-3-oxapentane

3-oxa-1,5-dichloropentane