(+/-)-methyl 2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]acrylate

Base Information

Chemical Name:(+/-)-methyl 2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]acrylate
CAS No.:868659-31-8
Molecular Formula:C₁₇H₂₅BrO₃Si
Molecular Weight:385.373
Hs Code.:

Synonyms:(+/-)-methyl 2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]acrylate

Suppliers and Price of (+/-)-methyl 2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]acrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (+/-)-methyl 2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]acrylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of (+/-)-methyl 2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]acrylate

There total 1 articles about (+/-)-methyl 2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 251320-24-8
2-[(4-bromo-phenyl)-hydroxy-methyl]-acrylic acid methyl ester

: 868659-31-8
(+/-)-methyl 2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]acrylate

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 18h;
DOI:10.1055/s-2005-872091

Reference yield: 78.0%

: 868659-31-8
(+/-)-methyl 2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]acrylate

: 868659-38-5
(+/-)-2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]-2-prop-2-en-1-ol

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; toluene; at -78 ℃; for 2h;
DOI:10.1055/s-2005-872091

Reference yield:

: 868659-31-8
(+/-)-methyl 2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]acrylate

: syn-(+/-)-2-[4-bromophenyl(tert-butyldimethylsilyloxy)methyl]-2-oxyranylmethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / DIBAL-H / CH₂Cl₂; toluene / 2 h / -78 °C

2: m-chloroperbenzoic acid / CH₂Cl₂ / 24 h / 20 °C

With diisobutylaluminium hydride; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; toluene;
DOI:10.1055/s-2005-872091