4-TERT-BUTYLAMINO-3-NITRO-BENZOIC ACID

Base Information

• Chemical Name: 4-TERT-BUTYLAMINO-3-NITRO-BENZOIC ACID
• CAS No.: 691363-50-5
• Molecular Formula: C₁₁H₁₄N₂O₄
• Molecular Weight: 238.243
• Mol file: 691363-50-5.mol

Synonyms:4-tert-butylamino-3-nitrobenzoic acid

Chemical Property of 4-TERT-BUTYLAMINO-3-NITRO-BENZOIC ACID

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

4-(tert-Butylamino)-3-nitrobenzoic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-TERT-BUTYLAMINO-3-NITRO-BENZOIC ACID

There total 2 articles about 4-TERT-BUTYLAMINO-3-NITRO-BENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-nitro-4-fluorobenzoic acid (453-71-4) + tert-butylamine (75-64-9) → 4-tert-butylamino-3-nitrobenzoic acid (691363-50-5)

Guidance literature:

With sodium hydrogencarbonate; at 150 ℃; for 0.333333h; microwave irradiation;

DOI:10.1021/jm051099t

Reference yield:

→ 4-tert-butylamino-3-nitrobenzoic acid (691363-50-5)

Guidance literature:

Reference yield:

4-tert-butylamino-3-nitrobenzoic acid (691363-50-5) → 3-amino-4-tert-butylamino-benzoic acid

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; at 20 ℃; for 3h; under 760 Torr;

DOI:10.1021/jm051099t

upstream raw materials:

3-nitro-4-fluorobenzoic acid

tert-butylamine

Refernces

• 1、 -. "BENZOTRIAZOLES AND METHODS OF PROPHYLAXIS OR TREATMENT OF METABOLIC-RELATED DISORDERS THEREOF". Page/Page column 56. . Retrieved 2008/06/13.