(1R,2S,3R,5S)-5-((3-amino-5-(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1,2,3,5-tetrayltetraacetate

Base Information

Chemical Name:(1R,2S,3R,5S)-5-((3-amino-5-(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1,2,3,5-tetrayltetraacetate
CAS No.:859224-90-1
Molecular Formula:C₂₃H₂₈N₂O₁₁
Molecular Weight:508.482
Hs Code.:

Synonyms:(1R,2S,3R,5S)-5-((3-amino-5-(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1,2,3,5-tetrayltetraacetate

Suppliers and Price of (1R,2S,3R,5S)-5-((3-amino-5-(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1,2,3,5-tetrayltetraacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2S,3R,5S)-5-((3-amino-5-(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1,2,3,5-tetrayltetraacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2S,3R,5S)-5-((3-amino-5-(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1,2,3,5-tetrayltetraacetate

There total 4 articles about (1R,2S,3R,5S)-5-((3-amino-5-(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1,2,3,5-tetrayltetraacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 32469-24-2
(1R,3R,4R,5R)-(-)-quinic acid tetraacetate

: 1949-55-9
methyl 3,5-diaminobenzoate

: 859224-90-1
(1R,2S,3R,5S)-5-((3-amino-5-(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1,2,3,5-tetrayltetraacetate

Guidance literature:: (1R,3R,4R,5R)-(-)-quinic acid tetraacetate; With benzotriazol-1-ol; In N,N-dimethyl-formamide; at 0 ℃; for 0.0833333h;

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

methyl 3,5-diaminobenzoate; In N,N-dimethyl-formamide; at 20 ℃; for 72h;

Reference yield:

: 1949-55-9
methyl 3,5-diaminobenzoate

: 87396-23-4
1,2,3-benzotriazol-1-yl D(-)-1,3,4,5-tetraacetoxycyclohexane-1-carboxylate

: 859224-90-1
(1R,2S,3R,5S)-5-((3-amino-5-(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1,2,3,5-tetrayltetraacetate

Guidance literature:: With triethylamine; In dichloromethane; N,N-dimethyl-formamide; at 0 - 20 ℃;
DOI:10.1021/jm050049l

Reference yield:

: 77-95-2
D-(-)-quinic acid

: 859224-90-1
(1R,2S,3R,5S)-5-((3-amino-5-(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1,2,3,5-tetrayltetraacetate

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 24 h / 20 °C

2: dicyclohexylcarbodiimide / CH₂Cl₂; tetrahydrofuran / 3 h / 0 - 20 °C

3: Et₃N / CH₂Cl₂; dimethylformamide / 0 - 20 °C

With pyridine; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm050049l