(1R,3R,4R,5R)-(-)-quinic acid tetraacetate

Base Information

• Chemical Name: (1R,3R,4R,5R)-(-)-quinic acid tetraacetate
• CAS No.: 32469-24-2
• Molecular Formula: C₁₅H₂₀O₁₀
• Molecular Weight: 360.318
• Mol file: 32469-24-2.mol

Synonyms:(1R,3R,4R,5R)-(-)-quinic acid tetraacetate

Chemical Property of (1R,3R,4R,5R)-(-)-quinic acid tetraacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,3R,4R,5R)-(-)-quinic acid tetraacetate

There total 6 articles about (1R,3R,4R,5R)-(-)-quinic acid tetraacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

D-(-)-quinic acid (77-95-2) + acetic anhydride (108-24-7) → (1R,3R,4R,5R)-(-)-quinic acid tetraacetate (32469-24-2)

Guidance literature:

With dmap; In pyridine; for 24h; Ambient temperature;

DOI:10.1002/hlca.19830660413

Reference yield: 91.0%

D-(-)-quinic acid (77-95-2) + acetic anhydride (108-24-7) + acetic acid (64-19-7,77671-22-8) → (1R,3R,4R,5R)-(-)-quinic acid tetraacetate (32469-24-2)

Guidance literature:

With perchloric acid; at 20 - 60 ℃;

Reference yield:

1,3,4,5-tetrahydroxy-cyclohexanecarboxylic acid (77-95-2,1010-25-9,7216-27-5,23804-29-7,23804-41-3,23804-44-6,36413-60-2,135558-83-7,135558-85-9,470-63-3,562-73-2,23804-34-4,23804-38-8) + acetic anhydride (108-24-7) → (1R,3R,4R,5R)-(-)-quinic acid tetraacetate (32469-24-2)

Guidance literature:

With zinc(II) chloride;

upstream raw materials:

acetic acid

1,3,4,5-tetrahydroxy-cyclohexanecarboxylic acid

acetic anhydride

D-(-)-quinic acid

Downstream raw materials:

(1R,3R,4S,5R)-1,3,4,5-tetraacetoxycyclohexane-1-carboxylic acid chloride

N-2-[N'-(1,3,4,5-tetraacetoxycyclohexanecarbonyl)]aminoethyl-N,N-di-n-tetradecylamine

C₆₀H₁₁₀N₄O₁₂

(1R,2S,3R,5S)-5-((3-amino-5-(methoxycarbonyl)phenyl)carbamoyl)cyclohexane-1,2,3,5-tetrayltetraacetate

Refernces

• 1、 Flores-Parra, Angelina,Paredes-Tepox, Concepcion,Joseph-Nathan, Pedro,Contreras, Rosalinda. "PREPARATION OF NEW QUINIC ACID BORON ESTERS IN APROTIC MEDIA". . p. 4137 - 4148. Retrieved 1990.
• 2、 -. "Novel quercetin derivatives, their preparation, pharmaceutical compositions containing them and their use". Page/Page column 11. . Retrieved 2012/07/03.