(3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane hydrochloride

Base Information

Chemical Name:(3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane hydrochloride
CAS No.:1227473-77-9
Molecular Formula:C₂₀H₂₂FNO*ClH
Molecular Weight:347.86
Hs Code.:

Synonyms:(3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane hydrochloride

Suppliers and Price of (3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane hydrochloride

Chemical Property:

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Technology Process of (3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane hydrochloride

There total 1 articles about (3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1227473-76-8
tert-butyl (3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane-8-carboxylate

: 1227473-77-9
(3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 3h;

Reference yield: 88.0%

: 1227473-77-9
(3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane hydrochloride

: 7693-46-1
4-Nitrophenyl chloroformate

: 1227473-78-0
4-nitrophenyl (3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane-8-carboxylate

Guidance literature:: (3R)-3-(4'-fluorobiphenyl-3-yl)-1-oxa-8-azaspiro[4.5]decane hydrochloride; With sodium hydrogencarbonate; In 1,4-dioxane; water; for 0.0833333h;

4-Nitrophenyl chloroformate; In 1,4-dioxane; water; at 20 ℃;