Technology Process of 3-(7-chloroheptyloxy)-6-(4-(11-(1,1,1,3,3,5,5-heptamethyltrisiloxanyl)undecyloxy)phenyl)pyridazine
There total 5 articles about 3-(7-chloroheptyloxy)-6-(4-(11-(1,1,1,3,3,5,5-heptamethyltrisiloxanyl)undecyloxy)phenyl)pyridazine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
di-isopropyl azodicarboxylate; triphenylphosphine;
In
tetrahydrofuran;
at 20 ℃;
Inert atmosphere;
DOI:10.1039/c1cc10344j
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / tetrahydrofuran / 1 h
1.2: 20 °C
2.1: hydrogenchloride / water; isopropyl alcohol / 5 h / 50 °C
3.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere
With
hydrogenchloride; di-isopropyl azodicarboxylate; sodium hydride; triphenylphosphine;
In
tetrahydrofuran; water; isopropyl alcohol;
3.1: Mitsunobu reaction;
DOI:10.1039/c1cc10344j
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tris-(dibenzylideneacetone)dipalladium(0); potassium phosphate; tricyclohexylphosphine / 1,4-dioxane; water / 18 h / 100 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran / 1 h
2.2: 20 °C
3.1: hydrogenchloride / water; isopropyl alcohol / 5 h / 50 °C
4.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C / Inert atmosphere
With
hydrogenchloride; potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0); di-isopropyl azodicarboxylate; sodium hydride; triphenylphosphine; tricyclohexylphosphine;
In
tetrahydrofuran; 1,4-dioxane; water; isopropyl alcohol;
4.1: Mitsunobu reaction;
DOI:10.1039/c1cc10344j
