2,2-bis(4-mehoxyphenyl)-4-(2,2-bis-(4-methoxyphenyl)vinyl)-6-nitrochromane

Base Information

• Chemical Name: 2,2-bis(4-mehoxyphenyl)-4-(2,2-bis-(4-methoxyphenyl)vinyl)-6-nitrochromane
• CAS No.: 33738-96-4
• Molecular Formula: C₃₉H₃₀O
• Molecular Weight: 514.667
• Mol file: 33738-96-4.mol

Synonyms:2,2-bis(4-mehoxyphenyl)-4-(2,2-bis-(4-methoxyphenyl)vinyl)-6-nitrochromane

Chemical Property of 2,2-bis(4-mehoxyphenyl)-4-(2,2-bis-(4-methoxyphenyl)vinyl)-6-nitrochromane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-bis(4-mehoxyphenyl)-4-(2,2-bis-(4-methoxyphenyl)vinyl)-6-nitrochromane

There total 3 articles about 2,2-bis(4-mehoxyphenyl)-4-(2,2-bis-(4-methoxyphenyl)vinyl)-6-nitrochromane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1,1-Diphenylethylene (530-48-3) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) → 2,2-bis(4-mehoxyphenyl)-4-(2,2-bis-(4-methoxyphenyl)vinyl)-6-nitrochromane (33738-96-4)

Guidance literature:

1,1-Diphenylethylene; 2-hydroxynaphthalene-1-carbaldehyde; With trifluorormethanesulfonic acid; trimethyl orthoformate; In toluene; at 20 ℃; for 1h; Inert atmosphere;

In toluene; at 100 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.tetlet.2018.03.090

Reference yield: 86.0%

1,1-Diphenylethylene (530-48-3) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) + trimethyl orthoformate (149-73-5) → 2,2-bis(4-mehoxyphenyl)-4-(2,2-bis-(4-methoxyphenyl)vinyl)-6-nitrochromane (33738-96-4)

Guidance literature:

1,1-Diphenylethylene; 2-hydroxynaphthalene-1-carbaldehyde; trimethyl orthoformate; With trifluorormethanesulfonic acid; In toluene; at 20 ℃; for 1h; Inert atmosphere;

In toluene; at 20 ℃; for 1h; regioselective reaction; Inert atmosphere;

DOI:10.1021/acs.joc.9b02036

Reference yield:

phenylmagnesium bromide → 2,2-bis(4-mehoxyphenyl)-4-(2,2-bis-(4-methoxyphenyl)vinyl)-6-nitrochromane (33738-96-4)

Guidance literature:

Erhitzen des Reaktionsprodukts mit Essigsaeure;

upstream raw materials:

1,1-Diphenylethylene

2-hydroxynaphthalene-1-carbaldehyde

trimethyl orthoformate