O-benzyldihydrofagaronine

Base Information

• Chemical Name: O-benzyldihydrofagaronine
• CAS No.: 96400-71-4
• Molecular Formula: C₂₈H₂₇NO₄
• Molecular Weight: 441.527
• Mol file: 96400-71-4.mol

Synonyms:O-benzyldihydrofagaronine

Chemical Property of O-benzyldihydrofagaronine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-benzyldihydrofagaronine

There total 1 articles about O-benzyldihydrofagaronine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-benzyloxy-3,8,9-trimethoxy-5-methyl-5,6-dihydrobenzo[c]phenanthridin-6-one (96400-70-3) → O-benzyldihydrofagaronine (96400-71-4)

Guidance literature:

With sodium tetrahydroborate; lithium aluminium tetrahydride; Yield given. Multistep reaction; 1.) THF, 2.) methanol;

DOI:10.1016/S0040-4039(01)81554-9

Reference yield: 93.0%

O-benzyldihydrofagaronine (96400-71-4) → O-benzylfagaronine chloride (113557-45-2)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone;

DOI:10.1016/S0040-4039(01)81554-9

Reference yield:

O-benzyldihydrofagaronine (96400-71-4) → fagaronine (52259-64-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / DDQ, 5percent aq. NaOH, cc.HCl / benzene / 3 h / Ambient temperature

2: 97 percent / 6N HCl / ethanol / 4 h / Heating

With hydrogenchloride; sodium hydroxide; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In ethanol; benzene;

DOI:10.1248/cpb.35.2348

upstream raw materials:

2-benzyloxy-3,8,9-trimethoxy-5-methyl-5,6-dihydrobenzo[c]phenanthridin-6-one

Downstream raw materials:

O-benzylfagaronine chloride

fagaronine