C₂₃H₂₀ClFO₂

Base Information

Chemical Name:C₂₃H₂₀ClFO₂
CAS No.:1090511-14-0
Molecular Formula:C₂₃H₂₀ClFO₂
Molecular Weight:382.862
Hs Code.:

C<sub>23</sub>H<sub>20</sub>ClFO<sub>2</sub>

Synonyms:C₂₃H₂₀ClFO₂

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Chemical Property of C₂₃H₂₀ClFO₂

Chemical Property:

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Technology Process of C₂₃H₂₀ClFO₂

There total 8 articles about C₂₃H₂₀ClFO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₇H₁₇BrO₂

: 160591-91-3
4-chloro-2-fluorophenylboronic acid

: 1090511-14-0
C₂₃H₂₀ClFO₂

Guidance literature:: With cesium fluoride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,2-dimethoxyethane; at 20 - 80 ℃; for 22.25h;

Reference yield:

: 14922-91-9
2-ethyl-5-bromoaniline

: 1090511-14-0
C₂₃H₂₀ClFO₂

Guidance literature:: Multi-step reaction with 5 steps

1.1: sulfuric acid / water / Heating / reflux

1.2: 0.75 h / 0 - 5 °C

1.3: 20 - 80 °C

2.1: isopropylmagnesium chloride / tetrahydrofuran / 1.33 h / -78 - 20 °C

2.2: 2 h / -78 - 20 °C

3.1: mercury(II) diacetate / chloroform / 5 h / 40 °C

4.1: dmap / chloroform / 4.33 h / 80 °C

5.1: cesium fluoride / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,2-dimethoxyethane / 22.25 h / 20 - 80 °C

With dmap; sulfuric acid; mercury(II) diacetate; isopropylmagnesium chloride; cesium fluoride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; 1,2-dimethoxyethane; chloroform; water; 5.1: Suzuki-Miyaura reaction;

Reference yield:

: 1033760-94-9
4-bromo-1-ethyl-2-iodobenzene

: 1090511-14-0
C₂₃H₂₀ClFO₂

Guidance literature:: Multi-step reaction with 4 steps

1.1: isopropylmagnesium chloride / tetrahydrofuran / 1.33 h / -78 - 20 °C

1.2: 2 h / -78 - 20 °C

2.1: mercury(II) diacetate / chloroform / 5 h / 40 °C

3.1: dmap / chloroform / 4.33 h / 80 °C

4.1: cesium fluoride / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,2-dimethoxyethane / 22.25 h / 20 - 80 °C

With dmap; mercury(II) diacetate; isopropylmagnesium chloride; cesium fluoride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; 1,2-dimethoxyethane; chloroform; 4.1: Suzuki-Miyaura reaction;