N-(N-(N-(benzyl-4-aminobenzoyl)-N-benzyl-4-aminobenzoyl)-N-isobutyl-4-aminobenzoyl)glycine

Base Information

Chemical Name:N-(N-(N-(benzyl-4-aminobenzoyl)-N-benzyl-4-aminobenzoyl)-N-isobutyl-4-aminobenzoyl)glycine
CAS No.:1233517-60-6
Molecular Formula:C₄₁H₄₀N₄O₅
Molecular Weight:668.792
Hs Code.:

Synonyms:N-(N-(N-(benzyl-4-aminobenzoyl)-N-benzyl-4-aminobenzoyl)-N-isobutyl-4-aminobenzoyl)glycine

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Chemical Property of N-(N-(N-(benzyl-4-aminobenzoyl)-N-benzyl-4-aminobenzoyl)-N-isobutyl-4-aminobenzoyl)glycine

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Technology Process of N-(N-(N-(benzyl-4-aminobenzoyl)-N-benzyl-4-aminobenzoyl)-N-isobutyl-4-aminobenzoyl)glycine

There total 4 articles about N-(N-(N-(benzyl-4-aminobenzoyl)-N-benzyl-4-aminobenzoyl)-N-isobutyl-4-aminobenzoyl)glycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₄₁H₃₉N₄O₅Pol

: 1233517-60-6
N-(N-(N-(benzyl-4-aminobenzoyl)-N-benzyl-4-aminobenzoyl)-N-isobutyl-4-aminobenzoyl)glycine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.666667h; Wang resin Automated synthesizer;
DOI:10.1016/j.bmc.2012.09.053

Reference yield:

: 1233518-05-2
4-((((9H-fluoren-9-yl)methoxy)carbonyl)(isobutyl)amino)benzoic acid

: 1233517-60-6
N-(N-(N-(benzyl-4-aminobenzoyl)-N-benzyl-4-aminobenzoyl)-N-isobutyl-4-aminobenzoyl)glycine

Guidance literature:: Multi-step reaction with 2 steps

1: 1-chloro-1-(dimethylamino)-2-methyl-1-propene / chloroform / 1 h / 20 °C

2: piperidine / N,N-dimethyl-formamide / 0.25 h

With piperidine; 1-chloro-1-(dimethylamino)-2-methyl-1-propene; In chloroform; N,N-dimethyl-formamide;
DOI:10.1002/anie.201410810

Reference yield:

: Fmoc-gly-wang resin

: C₂₆H₂₄ClNO₃

: C₂₉H₂₂ClNO₃

: 1233517-60-6
N-(N-(N-(benzyl-4-aminobenzoyl)-N-benzyl-4-aminobenzoyl)-N-isobutyl-4-aminobenzoyl)glycine

Guidance literature:: Fmoc-gly-wang resin; With piperidine; In N,N-dimethyl-formamide; for 0.25h; Wang resin

C₂₉H₂₂ClNO₃;

C₂₆H₂₄ClNO₃; C₂₉H₂₂ClNO₃; Further stages;
DOI:10.1002/anie.201410810